Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 4/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.49 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.49 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17385133 | 1.00 | SYK (0.57) | SYKRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL2760112 | 0.85 | SYK (0.59) | SYKRAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL29568574 | 0.83 | SYK (0.58) | SYKMAPTEGFRERBB2ERBB3 | |
| SCHEMBL21340419 | 0.83 | SYK (0.58) | SYKMAPTEGFRERBB2ERBB3 | |
| SCHEMBL29638125 | 0.82 | SYK (0.78) | SYKEGFRERBB2ERBB3ERBB4 | |
| SCHEMBL27096824 | 0.82 | SYK (0.61) | SYKRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL29195674 | 0.82 | CCR5 (0.51) | SYKALDH1A1CCR5KDM4EPKM | |
| SCHEMBL159323 | 0.82 | SYK (0.78) | SYKEGFRERBB2ERBB3ERBB4 | |
| Ammonia Solution, Strong SCHEMBL23859934 | 0.81 | SYK (0.76) | SYKEGFRERBB2ERBB3ERBB4 | |
| Hydrochloric Acid SCHEMBL6239858 | 0.81 | SYK (0.76) | SYKSMN1; SMN2EGFRERBB2ERBB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493439-B | Substituted acrylamide derivative, composition and application thereof | 深圳市塔吉瑞生物医药有限公司 | 2022-10-14 | — | — | CN | disclosed |