Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31370447 | 0.85 | MDM4 (0.54) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL31369498 | 0.85 | MDM4 (0.56) | MDM4TP53MDM2CASP3 | |
| SCHEMBL9170986 | 0.84 | MDM4 (0.56) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL29367434 | 0.83 | MDM4 (0.59) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL119455 | 0.83 | MDM4 (0.59) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL29440768 | 0.83 | MDM4 (0.59) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL29398498 | 0.83 | MDM4 (0.59) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL118169 | 0.83 | MDM4 (0.59) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL1228254 | 0.83 | MDM4 (0.59) | MDM4TP53MDM2CASP3SLC17A5 | |
| SCHEMBL29349650 | 0.83 | MDM4 (0.59) | MDM4TP53MDM2CASP3SLC17A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234867-A1 | SULFONAMIDE HAVING MMP 7-INHIBITING ACTION | 大正製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |