Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 8/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 2/20 | 0.44 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29990243 | 1.00 | RPS6KB1 (0.46) | RPS6KB1CHEK1KCNH2P2RX7FLT3 | |
| Trifluoroacetic Acid SCHEMBL6156921 | 0.84 | CACNA1B (0.45) | RPS6KB1P2RX7FLT3 | |
| SCHEMBL30032248 | 0.84 | SLC6A4 (0.47) | KCNH2P2RX7 | |
| SCHEMBL30033278 | 0.84 | SLC6A4 (0.47) | KCNH2P2RX7 | |
| SCHEMBL21460294 | 0.80 | SLC6A2 (0.44) | KCNH2P2RX7 | |
| SCHEMBL29990331 | 0.77 | RPS6KB1 (0.46) | RPS6KB1CHEK1KCNH2FLT3SYK | |
| SCHEMBL6156878 | 0.77 | RPS6KB1 (0.46) | RPS6KB1CHEK1KCNH2FLT3SYK | |
| SCHEMBL6153421 | 0.77 | AURKA (0.45) | RPS6KB1CHEK1KCNH2P2RX7FLT3 | |
| SCHEMBL30032904 | 0.77 | P2RX7 (0.51) | RPS6KB1CHEK1KCNH2P2RX7FLT3 | |
| SCHEMBL7668352 | 0.76 | P2RX7 (0.76) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234867-A1 | SULFONAMIDE HAVING MMP 7-INHIBITING ACTION | 大正製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |