Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.45 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.41 |
| ▸ | JAK1 | P23458 | 3/20 | 0.41 |
| ▸ | TYK2 | P29597 | 3/20 | 0.41 |
| ▸ | JAK3 | P52333 | 3/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156878 | 1.00 | RPS6KB1 (0.46) | RPS6KB1BTKPRKD1PRKD2FLT3 | |
| SCHEMBL6154228 | 0.91 | FLT3 (0.54) | RPS6KB1BTKFLT3CHEK1FPR3 | |
| SCHEMBL4144350 | 0.90 | IRAK4 (0.45) | RPS6KB1KDM1ASYKJAK2JAK1 | |
| Hydrochloric Acid SCHEMBL6153321 | 0.89 | IRAK4 (0.44) | RPS6KB1KDM1ASYKBCL9CTNNB1 | |
| SCHEMBL6153495 | 0.85 | SYK (0.45) | RPS6KB1PRKD1PRKD2FLT3CHEK1 | |
| SCHEMBL11891388 | 0.82 | ALDH1A1 (0.48) | MAPK14 | |
| SCHEMBL27932778 | 0.81 | SYK (0.48) | FLT3SYK | |
| SCHEMBL5392079 | 0.78 | PLK4 (0.56) | RPS6KB1PRKD2KDM1AFPR3FPR2 | |
| SCHEMBL9536802 | 0.78 | AXL (0.42) | RPS6KB1PRKD2CHEK1KDM1AFPR3 | |
| SCHEMBL12998885 | 0.78 | SYK (0.52) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234867-A1 | SULFONAMIDE HAVING MMP 7-INHIBITING ACTION | 大正製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |