Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1318530 | 0.73 | MEN1 (0.39) | SMN1; SMN2CYP19A1MEN1KMT2ALMNA | |
| SCHEMBL11951038 | 0.67 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP19A1MEN1KMT2ALMNA | |
| SCHEMBL14601299 | 0.67 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP19A1MEN1KMT2ALMNA | |
| SCHEMBL2534767 | 0.67 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP19A1MEN1KMT2ALMNA | |
| SCHEMBL1315523 | 0.67 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP19A1MEN1KMT2ALMNA | |
| SCHEMBL1315164 | 0.67 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP19A1MEN1KMT2ALMNA | |
| SCHEMBL7358289 | 0.66 | GAA (0.38) | SMN1; SMN2CYP19A1KMT2ALMNAADORA3 | |
| SCHEMBL7358282 | 0.66 | GAA (0.38) | SMN1; SMN2CYP19A1KMT2ALMNAADORA3 | |
| SCHEMBL577209 | 0.65 | CYP19A1 (0.56) | CYP19A1TSHR | |
| SCHEMBL5803864 | 0.65 | CA2 (0.40) | SMN1; SMN2CYP19A1KMT2ALMNAADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160158-B | Preparation method of chiral tertiary leucinol | 泰州天鸿生化科技有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-115160158-A | Preparation method of chiral tert-leucinol | 泰州天鸿生化科技有限公司 | 2022-10-11 | — | — | CN | disclosed |