SCHEMBL577209

SCHEMBL577209

O=C1OCC1c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 14/20 0.56
CFTR P13569 1/20 0.46
GOPC Q9HD26 1/20 0.46
TSHR P16473 1/20 0.44
CTRC Q99895 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2700586 0.89 CYP19A1 (0.58) CYP19A1
Alpha-Phenyl-Gamma-Butyrolactone SCHEMBL7909086 0.78 CYP19A1 (0.44) CYP19A1CFTRGOPCTSHRCTRC
Alpha-Phenyl-Gamma-Butyrolactone SCHEMBL6771142 0.78 CYP19A1 (0.44) CYP19A1CFTRGOPCTSHRCTRC
SCHEMBL576513 0.78 CYP19A1 (0.56) CYP19A1
SCHEMBL9492304 0.78 CYP19A1 (0.44) CYP19A1CFTRGOPCTSHRCTRC
Alpha-Phenyl-Gamma-Butyrolactone SCHEMBL576473 0.78 CYP19A1 (0.44) CYP19A1CFTRGOPCTSHRCTRC
SCHEMBL23914271 0.77 CYP19A1 (0.51) CYP19A1CFTRGOPCTSHRCTRC
SCHEMBL30674005 0.77 CYP19A1 (0.51) CYP19A1CFTRGOPCTSHRCTRC
SCHEMBL14159692 0.77 CTRC (0.43) CYP19A1CFTRGOPCTSHRCTRC
SCHEMBL576991 0.75 TP53 (0.42) CYP19A1CFTRGOPCTSHRCTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0888389-A4 PHOTOACTIVATABLE CHAIN TRANSFER AGENTS SURMODICS INC (US) 2001-03-14 EP claimed
EP-0888389-A1 PHOTOACTIVATABLE CHAIN TRANSFER AGENTS SurModics, Inc. (US) 1999-01-07 EP claimed
WO-1997034935-A1 PHOTOACTIVATABLE CHAIN TRANSFER AGENTS BSI CORPORATION (US) 1997-09-25 WO claimed
JP-9169753-A None JP disclosed
CN-118496831-B Water injection pitting corrosion inhibitor and preparation method thereof 克拉玛依市华油精细化工有限责任公司 2024-10-22 CN disclosed
CN-118496831-A Water injection pitting corrosion inhibitor and preparation method thereof 克拉玛依市华油精细化工有限责任公司 2024-08-16 CN disclosed
CN-110475776-B Tricyclic carboxamides for combating arthropods 拜耳作物科学股份公司 2024-03-19 CN disclosed
EP-3429567-B1 METHODS AND COMPOSITIONS FOR TREATING OBESITY AND/OR DIABETES AND FOR IDENTIFYING CANDIDATE TREATMENT AGENTS THE J DAVID GLADSTONE INST (US) 2024-01-10 EP disclosed
US-11814360-B2 Isocyanates, derivatives, and processes for producing the same NOVOMER, INC. (US) 2023-11-14 US disclosed
US-11814498-B2 Polylactone foams and methods of making the same NOVOMER, INC. (US) 2023-11-14 US disclosed
US-11814498-B2 Polylactone foams and methods of making the same NOVOMER, INC. (US) 2023-11-14 US disclosed
EP-0888389-B1 PHOTOACTIVATABLE CHAIN TRANSFER AGENTS SURMODICS INC (US) 2004-08-04 EP disclosed
EP-0888389-A4 PHOTOACTIVATABLE CHAIN TRANSFER AGENTS SURMODICS INC (US) 2001-03-14 EP disclosed
US-5942555-A Photoactivatable chain transfer agents and semi-telechelic photoactivatable polymers prepared therefrom SURMODICS, INC. (US) 1999-08-24 US disclosed
EP-0888389-A1 PHOTOACTIVATABLE CHAIN TRANSFER AGENTS SurModics, Inc. (US) 1999-01-07 EP disclosed
WO-1997034935-A1 PHOTOACTIVATABLE CHAIN TRANSFER AGENTS BSI CORPORATION (US) 1997-09-25 WO disclosed
JP-H09169753-A PRODUCTION OF COMPOUND OF 2-OXETANONES TOKUYAMA CORP 1997-06-30 JP disclosed
EP-0586575-A1 DEGRADABLE CELLULOSE POLYMERS BATTELLE MEMORIAL INSTITUTE (US) 1994-03-16 EP disclosed
WO-1992020738-A1 DEGRADABLE CELLULOSE POLYMERS BATTELLE MEMORIAL INSTITUTE (US) 1992-11-26 WO disclosed
US-4029718-A MOLDING MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11814360-B2 Isocyanates, derivatives, and processes for producing the same IDH1, IDH2, IDH3A CYP19A1 235/4885CFTR 4276/4885GOPC 2362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.