Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.54 |
| ▸ | C1S | P09871 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.49 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10373948 | 1.00 | BPTF (0.54) | BPTFC1SSMN1; SMN2HTTFAAH | |
| SCHEMBL255378 | 0.91 | ALDH1A1 (0.52) | BPTFC1SSMN1; SMN2HTTFAAH | |
| SCHEMBL30407553 | 0.91 | BPTF (0.51) | BPTFC1SSMN1; SMN2HTTFAAH | |
| SCHEMBL30167608 | 0.91 | ALDH1A1 (0.52) | BPTFC1SSMN1; SMN2HTTFAAH | |
| SCHEMBL7927182 | 0.90 | ADRA2C (0.65) | BPTFC1SSMN1; SMN2HTTFAAH | |
| SCHEMBL17476103 | 0.90 | SMN1; SMN2 (0.50) | BPTFC1SSMN1; SMN2HTTFAAH | |
| SCHEMBL3159432 | 0.89 | SMN1; SMN2 (0.50) | BPTFC1SSMN1; SMN2HTTFAAH | |
| SCHEMBL1267656 | 0.87 | BPTF (0.49) | BPTFC1SSMN1; SMN2HTTFAAH | |
| SCHEMBL22495327 | 0.87 | MAPT (0.67) | BPTFC1SSMN1; SMN2HTTPOLB | |
| SCHEMBL17787657 | 0.86 | LMNA (0.59) | BPTFHTTFAAHPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414216-B1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2020-10-21 | — | — | EP | disclosed |
| EP-3414216-B1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2020-10-21 | — | — | EP | disclosed |
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2019-02-07 | — | — | US | disclosed |
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | NAT1, AHR, ABL1 | BPTF 1292/4885C1S 1220/4885SMN1; SMN2 4575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.