SCHEMBL299917

SCHEMBL299917

C=CC/C(=C\c1ccccc1)c1ccc(S(C)(=O)=O)cc1

nearest known ligand 0.72

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.57
PTGS2 P35354 5/20 0.54
AKR1C2 P52895 1/20 0.50
AKR1C1 Q04828 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL299771 1.00 AKR1C3 (0.57) AKR1C3PTGS2AKR1C2AKR1C1
SCHEMBL9284800 0.84 MTNR1A (0.45) AKR1C1
SCHEMBL7756538 0.81 MTNR1A (0.49) AKR1C1
SCHEMBL7603630 0.81 MTNR1A (0.49) AKR1C1
SCHEMBL7603627 0.81 MTNR1A (0.49) AKR1C1
SCHEMBL14045283 0.78 AKR1C3 (0.55) AKR1C3PTGS2AKR1C2AKR1C1
SCHEMBL10339712 0.71 MEN1 (0.42) AKR1C3AKR1C1
SCHEMBL7604413 0.70 ESR1 (0.61) PTGS2
SCHEMBL7604418 0.70 ESR1 (0.61) PTGS2
SCHEMBL7758219 0.70 ESR1 (0.61) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240139027-A1 DIAGNOSTIC METHODS AND APPARATUS FORSIGHT VISION4, INC. 2024-05-02 US disclosed
US-11813196-B2 Diagnostic methods and apparatus FORSIGHT VISION4, INC. (US) 2023-11-14 US disclosed
US-20230338282-A1 POSTERIOR SEGMENT DRUG DELIVERY FORSIGHT VISION4, INC. 2023-10-26 US disclosed
US-11786396-B2 Injector apparatus and method for drug delivery FORSIGHT VISION4, INC. (US) 2023-10-17 US disclosed
EP-3799844-B1 IMPLANTABLE OCULAR DRUG DELIVERY DEVICES FORSIGHT VISION4 INC (US) 2023-10-04 EP disclosed
EP-4249059-A2 AN APPARATUS FOR COLLECTING A SAMPLE OF FLUID FROM A RESERVOIR CHAMBER OF A THERAPEUTIC DEVICE FOR THE EYE ForSight Vision4, Inc. (US) 2023-09-27 EP disclosed
US-20230225903-A1 IMPLANTABLE OCULAR DRUG DELIVERY DEVICES FORSIGHT VISION4, INC. 2023-07-20 US disclosed
EP-2726016-B1 AN APPARATUS FOR COLLECTING A SAMPLE OF FLUID FROM A RESERVOIR CHAMBER OF A THERAPEUTIC DEVICE FOR THE EYE FORSIGHT VISION4 INC (US) 2023-07-19 EP disclosed
US-11679027-B2 Combined drug delivery methods and apparatus FORSIGHT VISION4, INC. (US) 2023-06-20 US disclosed
US-11642310-B2 Posterior segment drug delivery FORSIGHT VISION4, INC. (US) 2023-05-09 US disclosed
US-20060264453-A1 Rapamycin formulations and methods of their use MACUSIGHT, INC. (US) 2006-11-23 US disclosed
US-20060257450-A1 Drug delivery systems for treatment of diseases or conditions SANTEN PHARMACEUTICAL CO., LTD. (JP) 2006-11-16 US disclosed
US-20060258698-A1 Liquid formulations for treatment of diseases or conditions SANTEN PHARMACEUTICAL CO., LTD. (JP) 2006-11-16 US disclosed
WO-2006102378-A2 DRUG DELIVERY SYSTEMS FOR TREATMENT OF DISEASES OR CONDITIONS MACUSIGHT, INC. (US) 2006-09-28 WO disclosed
WO-2006086750-A1 LIQUID FORMULATIONS FOR TREATMENT OF DISEASES OR CONDITIONS MACUSIGHT, INC. (US) 2006-08-17 WO disclosed
WO-2006086744-A1 FORMULATIONS FOR OCULAR TREATMENT MACUSIGHT, INC. (US) 2006-08-17 WO disclosed
US-20060182771-A1 Formulations for ocular treatment SANTEN PHARMACEUTICAL CO., LTD. (JP) 2006-08-17 US disclosed
EP-1682132-A1 TRANSSCLERAL DELIVERY Macusight, Inc. (US) 2006-07-26 EP disclosed
WO-2005027906-A1 TRANSSCLERAL DELIVERY MACUSIGHT, INC. (US) 2005-03-31 WO disclosed
US-20050064010-A1 Transscleral delivery SANTEN PHARMACEUTICAL CO., LTD. (JP) 2005-03-24 US disclosed