Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.61 |
| ▸ | NQO2 | P16083 | 4/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604413 | 1.00 | ESR1 (0.61) | ESR1ESR2NQO2PTGS1PTGS2 | |
| SCHEMBL7604418 | 1.00 | ESR1 (0.61) | ESR1ESR2NQO2PTGS1PTGS2 | |
| SCHEMBL9245165 | 0.83 | ESR1 (0.42) | ESR1ESR2NQO2 | |
| SCHEMBL9245167 | 0.83 | ESR1 (0.42) | ESR1ESR2NQO2 | |
| SCHEMBL9284800 | 0.82 | MTNR1A (0.45) | ESR1ESR2ALDH1A1MEN1KMT2A | |
| SCHEMBL7756538 | 0.78 | MTNR1A (0.49) | ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7603627 | 0.78 | MTNR1A (0.49) | ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7603630 | 0.78 | MTNR1A (0.49) | ESR1ALDH1A1MEN1KMT2A | |
| SCHEMBL9113341 | 0.76 | ESR1 (1.00) | ESR1ESR2NQO2PTGS1PTGS2 | |
| SCHEMBL574346 | 0.76 | ESR1 (1.00) | ESR1ESR2NQO2PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927148-B1 | PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE WITH REDUCED DIMER FORMATION | MICHIGAN MOLECULAR INST (US) | 2001-03-07 | — | — | EP | claimed |
| EP-0927148-B1 | PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENE WITH REDUCED DIMER FORMATION | MICHIGAN MOLECULAR INST (US) | 2001-03-07 | — | — | EP | disclosed |