SCHEMBL29992134

SCHEMBL29992134

COc1c(N)cncc1-c1cnn(C2CC2)n1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27172210 1.00 CYP11B1 (0.33) CYP11B1CYP11B2
SCHEMBL24824796 0.83 PIK3CA (0.33) CYP11B2
SCHEMBL24822783 0.82 PIK3CA (0.31) CYP11B1CYP11B2
SCHEMBL24823464 0.81 NLRP3 (0.33) CYP11B1CYP11B2
SCHEMBL24776723 0.76 PIK3CA (0.34)
SCHEMBL27172208 0.74 PIK3CA (0.38)
SCHEMBL24824803 0.73 TLR8 (0.38) CYP11B1CYP11B2
SCHEMBL24823026 0.73 ALOX5AP (0.31)
SCHEMBL24823462 0.72 MAOA (0.33)
SCHEMBL24823005 0.71 CYP11B1 (0.39) CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4337656-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS Bristol-Myers Squibb Company (US) 2024-03-20 EP disclosed
CN-117321045-A Substituted heterocyclic compounds 百时美施贵宝公司 2023-12-29 CN disclosed
WO-2022241175-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2022-11-17 WO disclosed