SCHEMBL2999253

SCHEMBL2999253

O=C1C(=O)c2c(O)cccc2-c2ccccc21

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.71
MAPT P10636 8/20 0.68
MAPK1 P28482 4/20 0.68
ALDH1A1 P00352 4/20 0.68
TDP1 Q9NUW8 4/20 0.68
LMNA P02545 3/20 0.68
SMN1; SMN2 Q16637 3/20 0.68
HPGD P15428 3/20 0.68
HTT P42858 2/20 0.68
ALOX15 P16050 2/20 0.68
HSD17B10 Q99714 2/20 0.68
TSHR P16473 2/20 0.68
MAOB P27338 1/20 0.68
KMT2A Q03164 6/20 0.64
MEN1 O00255 5/20 0.64
KDM4E B2RXH2 5/20 0.59
RECQL P46063 5/20 0.59
POLB P06746 4/20 0.59
BLM P54132 3/20 0.59
APAF1 O14727 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1039833 0.95 MAOA (0.78) MAOAMAPTMAPK1ALDH1A1TDP1
SCHEMBL31253342 0.95 MAOA (0.78) MAOAMAPTMAPK1ALDH1A1TDP1
SCHEMBL875843 0.88 MAPT (0.86) MAOAMAPTMAPK1ALDH1A1TDP1
1-Hydroxyanthraquinone SCHEMBL30912125 0.86 MAOA (0.86) MAOAMAPTMAPK1ALDH1A1TDP1
SCHEMBL9350943 0.86 MAOA (0.71) MAOAMAPTMAPK1ALDH1A1TDP1
Anthrarufin SCHEMBL25355428 0.86 MAOA (0.86) MAOAMAPTMAPK1ALDH1A1TDP1
1-Hydroxyanthraquinone SCHEMBL145303 0.86 MAOA (0.86) MAOAMAPTMAPK1ALDH1A1TDP1
Naphthazalin SCHEMBL8047605 0.85 MAPT (0.62) MAOAMAPTMAPK1ALDH1A1TDP1
Anthrarufin SCHEMBL11422341 0.84 MAPT (0.83) MAOAMAPTMAPK1ALDH1A1TDP1
1-Hydroxyanthraquinone SCHEMBL1893347 0.84 MAOA (0.83) MAOAMAPTMAPK1ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3979320-A Liquid crystal composition HODOGAYA CHEMICAL CO., LTD. (JA) 1976-09-07 US claimed
US-3975285-A LONG LIFE DYNAMIC LIGHT SCATTERING PROPERTIES HODOGAYA CHEMICAL CO., LTD. (JA) 1976-08-17 US claimed
US-20100180937-A1 HOLOGRAPHIC ENERGY-COLLECTING MEDIUM AND ASSOCIATED DEVICE GENERAL ELECTRIC COMPANY (US) 2010-07-22 US disclosed
US-4933399-A COATING INSIDE OF VESSEL WITH A CATIONIC DYE, DRYING, COATING WITH AN ANIONIC OR AMPHOTERIC POLYMER OR A HYDROXYL-CONTAINING COMPOUND IN A SOLVENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-06-12 US disclosed
EP-0320227-A2 Method of preventing polymer-scale formation Shin-Etsu Chemical Co., Ltd. (JP) 1989-06-14 EP disclosed
US-3979320-A Liquid crystal composition HODOGAYA CHEMICAL CO., LTD. (JA) 1976-09-07 US disclosed
US-3975285-A LONG LIFE DYNAMIC LIGHT SCATTERING PROPERTIES HODOGAYA CHEMICAL CO., LTD. (JA) 1976-08-17 US disclosed