Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 10/20 | 0.37 |
| ▸ | CCL2 | P13500 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19951542 | 1.00 | MELK (0.38) | MELKBRD4CCL2GABRA2PTGDR2 | |
| SCHEMBL19962969 | 0.91 | MELK (0.35) | MELKBRD4CCL2GABRA2CREBBP | |
| SCHEMBL19962962 | 0.90 | MELK (0.37) | MELKBRD4GABRA2CREBBPKCNH2 | |
| SCHEMBL19962970 | 0.90 | MELK (0.34) | MELKBRD4CCL2RIPK2 | |
| SCHEMBL19962968 | 0.89 | MELK (0.36) | MELKBRD4GABRA2CREBBPKCNH2 | |
| SCHEMBL21130654 | 0.88 | NR3C1 (0.35) | MELKCREBBPKCNH2RIPK2 | |
| SCHEMBL19962966 | 0.88 | MELK (0.35) | MELKGABRA2KCNH2RIPK2 | |
| SCHEMBL19962903 | 0.87 | TSHR (0.40) | — | |
| SCHEMBL21130655 | 0.87 | MELK (0.32) | MELKBRD4CCL2RIPK2 | |
| SCHEMBL19962964 | 0.86 | DRD2 (0.37) | MELKBRD4CCL2GABRA2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072861-B | Disubstituted pyrazoles for the treatment of diseases | FGH生物科技公司 | 2022-11-11 | — | — | CN | disclosed |