Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | DDO | Q99489 | 1/20 | 0.55 |
| ▸ | ITK | Q08881 | 4/20 | 0.51 |
| ▸ | AHR | P35869 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711446 | 0.84 | NPC1 (0.63) | DAODDOITKKDM4EMAPT | |
| SCHEMBL31404848 | 0.84 | NPC1 (0.63) | DAODDOITKKDM4EMAPT | |
| SCHEMBL7649750 | 0.82 | ALDH1A1 (0.62) | DAODDOITKAHRKDM4E | |
| SCHEMBL28639213 | 0.81 | ITK (0.46) | DAODDOITKAHRFLT3 | |
| SCHEMBL29993613 | 0.80 | DAO (0.46) | DAODDOITKAHRKDM4E | |
| SCHEMBL17422758 | 0.80 | CYP19A1 (0.50) | DAODDOITKAHRKDM4E | |
| SCHEMBL28809806 | 0.80 | NPC1 (0.58) | DAODDOITKKDM4EMAPT | |
| SCHEMBL6480005 | 0.78 | ITK (0.47) | DAODDOITKAHRFLT3 | |
| SCHEMBL8305347 | 0.78 | MAPT (0.77) | DAODDOITKKDM4EMAPT | |
| SCHEMBL2993745 | 0.77 | KEAP1 (0.52) | DAODDOITKAHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440507-B | Compound as apoptosis protein inhibitor and application thereof | 南京圣和药物研发有限公司 | 2022-10-18 | — | — | CN | disclosed |