Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.75 |
| ▸ | RAB9A | P51151 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | CA12 | O43570 | 2/20 | 0.63 |
| ▸ | CA9 | Q16790 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TSPO | P30536 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3163935 | 0.84 | NPC1 (0.75) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL1516137 | 0.84 | NPC1 (0.75) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL544271 | 0.84 | NPC1 (0.75) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL544272 | 0.84 | NPC1 (0.75) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL180384 | 0.83 | NPC1 (0.73) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL991685 | 0.82 | RAB9A (0.72) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL3301637 | 0.82 | NPC1 (0.72) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL6632648 | 0.82 | AOC3 (0.73) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL11192974 | 0.82 | NPC1 (0.85) | NPC1RAB9AKMT2ACA12CA9 | |
| SCHEMBL4939224 | 0.82 | RAB9A (0.72) | NPC1RAB9AKMT2ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334285-A1 | CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS | Kare Chemical Technologies Inc. (CA) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022232931-A1 | CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS | KARE CHEMICAL TECHNOLOGIES INC. (CA) | 2022-11-10 | — | — | WO | disclosed |