SCHEMBL544271

SCHEMBL544271

CN(Cc1ccccc1)C(=O)C[O]

nearest known ligand 0.75

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.75
RAB9A P51151 3/20 0.75
KMT2A Q03164 3/20 0.68
CA12 O43570 2/20 0.63
CA9 Q16790 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.62
ALDH1A1 P00352 1/20 0.58
POLB P06746 1/20 0.58
TSPO P30536 1/20 0.57
MEN1 O00255 1/20 0.56
MAPK1 P28482 1/20 0.55
HPGD P15428 2/20 0.54
RIPK1 Q13546 1/20 0.54
AOC3 Q16853 1/20 0.53
MGLL Q99685 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4939224 0.86 RAB9A (0.72) NPC1RAB9AKMT2ACA12CA9
SCHEMBL3163935 0.84 NPC1 (0.75) NPC1RAB9AKMT2ACA12CA9
SCHEMBL544272 0.84 NPC1 (0.75) NPC1RAB9AKMT2ACA12CA9
SCHEMBL1516137 0.84 NPC1 (0.75) NPC1RAB9AKMT2ACA12CA9
SCHEMBL29993175 0.84 NPC1 (0.75) NPC1RAB9AKMT2ACA12CA9
SCHEMBL180384 0.83 NPC1 (0.73) NPC1RAB9AKMT2ACA12CA9
SCHEMBL5145639 0.82 NPC1 (0.72) NPC1RAB9AKMT2ACA12CA9
SCHEMBL3301637 0.82 NPC1 (0.72) NPC1RAB9AKMT2ACA12CA9
SCHEMBL991685 0.82 RAB9A (0.72) NPC1RAB9AKMT2ACA12CA9
SCHEMBL6632648 0.82 AOC3 (0.73) NPC1RAB9AKMT2ACA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2354187-B1 DISPERSED COMPOSITION, POLYMERIZABLE COMPOSITION, LIGHT SHIELDING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, LIQUID CRYSTAL DISPLAY DEVICE, WAFER-LEVEL LENS, AND IMAGING UNIT FUJIFILM CORP (JP) 2016-03-02 EP disclosed
US-9110205-B2 Black curable composition, light-shielding color filter, light-shielding film and method for manufacturing the same, wafer level lens, and solid-state imaging device FUJIFILM CORPORATION (JP) 2015-08-18 US disclosed
EP-2037323-B1 Photosensitive compositions FUJIFILM CORP (JP) 2014-12-10 EP disclosed
US-8895909-B2 Photosensitive resin composition, light-shielding color filter, method of producing the same and solid-state image sensor FUJIFILM CORPORATION (JP) 2014-11-25 US disclosed
US-8872099-B2 Solid-state image sensor including a light-shielding color filter formed from a photosensitive resin composition, photosensitive resin composition and method of producing a light-shielding color filter FUJIFILM CORPORATION (JP) 2014-10-28 US disclosed
US-8828629-B2 Black curable composition, light-shielding color filter for a solid-state imaging device and method of producing the same, solid-state imaging device, wafer level lens, and camera module FUJIFILM CORPORATION (JP) 2014-09-09 US disclosed
US-8728686-B2 Photosensitive compositions, curable compositions, novel compounds, photopolymerizable compositions, color filters, and planographic printing plate precursors FUJIFILM CORPORATION (JP) 2014-05-20 US disclosed
US-20130306919-A1 PHOTOSENSITIVE RESIN COMPOSITION, LIGHT-SHIELDING COLOR FILTER, METHOD OF PRODUCING THE SAME AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2013-11-21 US disclosed
US-8470502-B2 Photosensitive resin composition, color filter and method of producing the same, and solid-state imaging device FUJIFILM CORPORATION (JP) 2013-06-25 US disclosed
US-20130028587-A1 BLACK CURABLE COMPOSITION, LIGHT-SHIELDING COLOR FILTER FOR A SOLID-STATE IMAGING DEVICE AND METHOD OF PRODUCING THE SAME, SOLID-STATE IMAGING DEVICE, WAFER LEVEL LENS, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2013-01-31 US disclosed
US-20030077542-A1 Photopolymerizable composition, recording material and image forming method FUJI PHOTO FILM CO., LTD. 2003-04-24 US disclosed
US-6495546-B1 SUCH AS 1-(N-BENZYL-N-(3-METHOXY-6,7,8,9-TETRAHYDRO-5H-BENZO-CYCLOHEPTEN-6-YL)AMINO)-3-PHENOXY-2-PROPANOL; ADRENERGIC RECEPTOR AGONISTS; ANTIULCEROUS, LIPOLYTIC, ANTIURINARY INCONTINENCE AND ANTIPOLLAKIURIA ACTIVITIES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-12-17 US disclosed
US-20020120148-A1 Propanolamine derivatives FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 2002-08-29 US disclosed
US-20020065194-A1 Guanidine compound and heat sensitive recording material FUJI PHOTO FILM CO., LTD. 2002-05-30 US disclosed
US-6348529-B1 THERMOSENSITIVE RECORDING WITH TWO ETHERS AND TWO GUANIDINE GROUPS FUJI PHOTO FILM CO., LTD. (JP) 2002-02-19 US disclosed
US-6329116-B1 CYAN COUPLER AND A DIAZONIUM SALT COMPOUND, EXCELLENT SHELF LIFE, IMAGE LIGHT-RESISTANCE, IMAGE FIXING, EXCELLENT HUE AND COLOR DENSITY, PREFERABLY MICROENCAPSULATED IN POLYURETHANE OR POLYUREA FUJI PHOTO FILM CO., LTD. (JP) 2001-12-11 US disclosed
US-6316605-B1 FOR USE IN RECORDING MATERIALS FOR THERMAL TRANSFER RECORDING, INK JET RECORDING FUJI PHOTO FILM CO., LTD. (JP) 2001-11-13 US disclosed
EP-1070046-A1 PROPANOLAMINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-01-24 EP disclosed
WO-1999051564-A1 PROPANOLAMINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-10-14 WO disclosed
US-5925489-A CONTAINING DIAZONIUM SALT AND PYRROLOPYRIMIDINE COUPLER WHICH REACT WHEN HEATED TO DEVELOP VIOLET TO CYAN COLORS, IMAGE QUALITY AND STABILITY, SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1999-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020120148-A1 Propanolamine derivatives AMY2A, PNMT, PNLIP NPC1 3445/4885RAB9A 2413/4885KMT2A 2618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.