SCHEMBL29993176

SCHEMBL29993176

CC(C)(C)[Si](C)(C)Oc1cccc2c1CCC2=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.43
ADRB1 P08588 1/20 0.43
HTR1A P08908 1/20 0.43
ADRB3 P13945 1/20 0.43
TSHR P16473 1/20 0.43
SLC6A4 P31645 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
ALDH1A1 P00352 3/20 0.40
GAA P10253 2/20 0.40
ABCB1 P08183 2/20 0.40
KDM4E B2RXH2 3/20 0.40
HPGD P15428 2/20 0.40
S1PR1 P21453 1/20 0.38
BRAF P15056 1/20 0.38
CYP19A1 P11511 1/20 0.36
PDE4D Q08499 1/20 0.36
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
S100A4 P26447 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1660912 1.00 ADRB2 (0.43) ADRB2ADRB1HTR1AADRB3TSHR
SCHEMBL2487204 0.91 ADRB2 (0.52) ADRB2ADRB1HTR1AADRB3TSHR
SCHEMBL29588862 0.91 ADRB2 (0.52) ADRB2ADRB1HTR1AADRB3TSHR
SCHEMBL5153891 0.80 ADRB2 (0.37) ADRB2ADRB1HTR1AADRB3TSHR
SCHEMBL16593838 0.76 PTK2 (0.39) ABCB1PREP
SCHEMBL430401 0.75 ADRB2 (0.53) ADRB2ADRB1HTR1A
SCHEMBL165220 0.75 KDM4E (0.61) ALDH1A1GAAABCB1KDM4EHPGD
SCHEMBL29506042 0.75 KDM4E (0.61) ALDH1A1GAAABCB1KDM4EHPGD
SCHEMBL7096400 0.73 HPGD (0.38) ADRB2ADRB1HTR1AADRB3TSHR
SCHEMBL7096401 0.73 HPGD (0.38) ADRB2ADRB1HTR1AADRB3TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110785413-B Pyrimidinoxybenzo-fused compounds as herbicides FMC公司 2024-08-02 CN disclosed
CN-117642392-A Preparation and application of compounds with immunoregulation function 上海轶诺药业有限公司 2024-03-01 CN disclosed
CN-115433210-A Preparation and application of compound with immunoregulation function 上海轶诺药业有限公司 2022-12-06 CN disclosed