Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993176 | 1.00 | ADRB2 (0.43) | ADRB2ADRB1HTR1AADRB3TSHR | |
| SCHEMBL2487204 | 0.91 | ADRB2 (0.52) | ADRB2ADRB1HTR1AADRB3TSHR | |
| SCHEMBL29588862 | 0.91 | ADRB2 (0.52) | ADRB2ADRB1HTR1AADRB3TSHR | |
| SCHEMBL5153891 | 0.80 | ADRB2 (0.37) | ADRB2ADRB1HTR1AADRB3TSHR | |
| SCHEMBL16593838 | 0.76 | PTK2 (0.39) | ABCB1PREP | |
| SCHEMBL430401 | 0.75 | ADRB2 (0.53) | ADRB2ADRB1HTR1A | |
| SCHEMBL165220 | 0.75 | KDM4E (0.61) | ALDH1A1GAAABCB1KDM4EHPGD | |
| SCHEMBL29506042 | 0.75 | KDM4E (0.61) | ALDH1A1GAAABCB1KDM4EHPGD | |
| SCHEMBL7096400 | 0.73 | HPGD (0.38) | ADRB2ADRB1HTR1AADRB3TSHR | |
| SCHEMBL7096401 | 0.73 | HPGD (0.38) | ADRB2ADRB1HTR1AADRB3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590062-B2 | PD-1/PD-L1 inhibitors | GILEAD SCIENCES, INC. (US) | 2026-03-31 | — | — | US | disclosed |
| CN-117642392-A | Preparation and application of compounds with immunoregulation function | 上海轶诺药业有限公司 | 2024-03-01 | — | — | CN | disclosed |
| EP-3619206-B1 | PYRIMIDINYLOXY BENZO-FUSED COMPOUNDS AS HERBICIDES | FMC CORP (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022253327-A1 | PREPARATION AND USE OF COMPOUND HAVING IMMUNOMODULATORY FUNCTION | 上海轶诺药业有限公司 | 2022-12-08 | — | — | WO | disclosed |
| CN-115433210-A | Preparation and application of compound with immunoregulation function | 上海轶诺药业有限公司 | 2022-12-06 | — | — | CN | disclosed |
| US-11427549-B2 | Pyrimidinyloxy benzo-fused compounds as herbicides | FMC CORPORATION (US) | 2022-08-30 | — | — | US | disclosed |
| EP-4026835-A2 | PD-1/PD-L1 INHIBITORS | Gilead Sciences, Inc. (US) | 2022-07-13 | — | — | EP | disclosed |
| EP-4026835-A2 | PD-1/PD-L1 INHIBITORS | Gilead Sciences, Inc. (US) | 2022-07-13 | — | — | EP | disclosed |
| EP-3612525-B1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-27 | — | — | EP | disclosed |
| EP-3612525-B1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-27 | — | — | EP | disclosed |
| US-7074863-B2 | Metallocene catalysts containing an idenyl moiety substituted at the 4,-5,-6- or 7-position by a siloxy or germyloxy group | BOREALIS TECHNOLOGY OY (FI) | 2006-07-11 | — | — | US | disclosed |
| US-20040152882-A1 | Metallocene catalysts containing an idenyl moiety substituted at the 4,-5,-6- or 7-position by a siloxy or germyloxy group | BOREALIS TECHNOLOGY OY (FI) | 2004-08-05 | — | — | US | disclosed |
| EP-1401880-A1 | METALLOCENE CATALYSTS CONTAINING AN INDENYL MOIETY SUBSTITUTED AT THE 4-, 5-, 6- OR 7-POSITION BY A SILOXY OR GERMYLOXY GROUP | Borealis Technology Oy (FI) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003000744-A1 | METALLOCENE CATALYSTS CONTAINING AN IDENYL MOIETY SUBSTITUTED AT THE 4-, 5-, 6- OR 7-POSITION BY A SILOXY OR GERMYLOXY GROUP | BOREALIS TECHNOLOGY OY (FI) | 2003-01-03 | — | — | WO | disclosed |
| EP-0288962-B1 | Aryl-aralkyl ethers, processes for their preparation and pharmaceutical composition comprising them | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-07-13 | — | — | EP | disclosed |
| US-5061718-A | BENZOTHIAZOLYLMETHOXY COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND THEIR USE AS ANTI-INFLAMMATORY OR ANTI-ALLERGENIC AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| US-5045548-A | Lipoxygenase inhibitors | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| US-4965274-A | Antiallergen, antiinflammatory agent; lipoxygenase | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-10-23 | — | — | US | disclosed |
| US-4923881-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS | Fujisawa Phatmaceutical Co., Ltd. (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0288962-A2 | Aryl-aralkyl ethers, processes for their preparation and pharmaceutical composition comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11427549-B2 | Pyrimidinyloxy benzo-fused compounds as herbicides | DDT, CNPY2, CBR3 | ADRB2 1961/4885ADRB1 2016/4885HTR1A 3758/4885 |
| US-12590062-B2 | PD-1/PD-L1 inhibitors | CD274, PDCD1LG2, PDCD1 | ADRB2 195/4885ADRB1 76/4885HTR1A 1813/4885 |
| US-20040152882-A1 | Metallocene catalysts containing an idenyl moiety substituted at the 4,-5,-6- or 7-position by a siloxy or germyloxy group | IPO4, GEMIN4, GEMIN5 | ADRB2 4335/4885ADRB1 4713/4885HTR1A 1501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.