Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.38 |
| ▸ | BIRC7 | Q96CA5 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12944882 | 1.00 | POLB (0.44) | POLBTGM2DRD4SIGMAR1HTR6 | |
| SCHEMBL5019942 | 1.00 | POLB (0.44) | POLBTGM2DRD4SIGMAR1HTR6 | |
| SCHEMBL943113 | 1.00 | POLB (0.44) | POLBTGM2DRD4SIGMAR1HTR6 | |
| SCHEMBL5019959 | 0.91 | POLB (0.43) | POLBTGM2DRD4SIGMAR1HTR6 | |
| SCHEMBL19540487 | 0.91 | TGM2 (0.43) | POLBTGM2DRD4SIGMAR1HTR6 | |
| SCHEMBL16791288 | 0.90 | TGM2 (0.42) | POLBTGM2DRD4SIGMAR1HTR6 | |
| SCHEMBL5019943 | 0.88 | TGM2 (0.41) | POLBTGM2DRD4SIGMAR1HTR6 | |
| SCHEMBL29993724 | 0.88 | TGM2 (0.41) | POLBTGM2DRD4SIGMAR1HTR6 | |
| SCHEMBL12944880 | 0.88 | TGM2 (0.41) | POLBTGM2DRD4SIGMAR1HTR6 | |
| SCHEMBL946384 | 0.88 | TGM2 (0.41) | POLBTGM2DRD4SIGMAR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440507-B | Compound as apoptosis protein inhibitor and application thereof | 南京圣和药物研发有限公司 | 2022-10-18 | — | — | CN | disclosed |