Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.54 |
| ▸ | KDM1A | O60341 | 3/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005337 | 0.88 | PARP10 (0.51) | TRPV4KDM1APARP10PARP15FFAR4 | |
| SCHEMBL8005329 | 0.88 | PARP10 (0.51) | TRPV4KDM1APARP10PARP15FFAR4 | |
| SCHEMBL9345940 | 0.87 | TRPV4 (0.43) | TRPV4KDM1ACYP11B1CYP11B2 | |
| SCHEMBL9591416 | 0.87 | TRPV4 (0.43) | TRPV4KDM1ACYP11B1CYP11B2 | |
| SCHEMBL8154702 | 0.86 | TRPV4 (0.52) | TRPV4KDM1APARP10PARP15SLC6A2 | |
| SCHEMBL8154704 | 0.86 | TRPV4 (0.52) | TRPV4KDM1APARP10PARP15SLC6A2 | |
| SCHEMBL18722089 | 0.86 | PARP10 (0.58) | TRPV4KDM1APARP10PARP15SLC6A2 | |
| SCHEMBL8020669 | 0.85 | TRPV4 (0.45) | TRPV4KDM1APARP10PARP15HPGD | |
| SCHEMBL8016037 | 0.85 | TRPV4 (0.45) | TRPV4KDM1APARP10PARP15HPGD | |
| SCHEMBL8020665 | 0.85 | TRPV4 (0.45) | TRPV4KDM1APARP10PARP15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |
| WO-2012025182-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-03-01 | — | — | WO | disclosed |
| EP-2423294-A1 | Switch element comprising a liquid-crystalline medium | Merck Patent GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |