Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28887108 | 1.00 | PIK3CD (0.50) | PIK3CDHCRTR1HCRTR2PDE3BPDE3A | |
| SCHEMBL26774278 | 0.80 | HCRTR1 (0.48) | PIK3CDHCRTR1HCRTR2PDE3BPDE3A | |
| SCHEMBL26774280 | 0.80 | HCRTR1 (0.46) | PIK3CDHCRTR1HCRTR2PDE3BPDE3A | |
| SCHEMBL26774466 | 0.80 | HCRTR1 (0.46) | PIK3CDHCRTR1HCRTR2PDE3BPDE3A | |
| SCHEMBL26774465 | 0.80 | HCRTR1 (0.48) | PIK3CDHCRTR1HCRTR2PDE3BPDE3A | |
| SCHEMBL26773358 | 0.79 | OXTR (0.48) | HCRTR1HCRTR2PDE3BPDE3APDE10A | |
| SCHEMBL10107364 | 0.78 | DRD2 (0.51) | PIK3CDAVPR1AHRH3PIK3CAOXTR | |
| SCHEMBL29868881 | 0.77 | HRH3 (0.49) | PIK3CDAVPR1AHRH3 | |
| SCHEMBL29483156 | 0.77 | HRH3 (0.52) | PDE3BPDE3APDE10AHRH3RET | |
| SCHEMBL29373138 | 0.77 | HRH3 (0.49) | PIK3CDAVPR1AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115335050-A | Compounds and compositions for treating skin conditions | 卡玛瑞制药有限公司 | 2022-11-11 | — | — | CN | disclosed |