Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.53 |
| ▸ | LOX | P28300 | 1/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22264304 | 1.00 | LOXL2 (0.53) | LOXL2LOXKCNQ2ADAMTS4MMP13 | |
| SCHEMBL13363420 | 0.84 | HCRTR1 (0.37) | LOXL2LOXKCNQ2ADAMTS4MMP13 | |
| SCHEMBL501336 | 0.80 | LOXL2 (0.49) | LOXL2KCNQ2CA2CDK2 | |
| SCHEMBL29962624 | 0.80 | LOXL2 (0.49) | LOXL2KCNQ2CA2CDK2 | |
| SCHEMBL22277951 | 0.79 | LOXL2 (0.61) | LOXL2LOXKCNQ2ADAMTS4MMP13 | |
| SCHEMBL615622 | 0.78 | KCNQ2 (0.43) | LOXL2LOXKCNQ2ADAMTS4MMP13 | |
| SCHEMBL22775173 | 0.77 | CA2 (0.42) | KMT2APTGS2CA2MRGPRX4 | |
| SCHEMBL3116042 | 0.76 | CYP1A2 (0.39) | LOXL2LOXTYMSCA2 | |
| SCHEMBL1670067 | 0.76 | PARP1 (0.35) | LOXL2LOXRXRAGRIN1GRIN2B | |
| SCHEMBL5793683 | 0.76 | RECQL (0.49) | LOXL2LOXPTGS2CA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288433-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |
| WO-2022167819-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2022-08-11 | — | — | WO | disclosed |