Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.69 |
| ▸ | PARP1 | P09874 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826724 | 0.82 | TNKS2 (1.00) | TNKS2PARP1KMT2APDE10AMEN1 | |
| SCHEMBL30176850 | 0.82 | TNKS2 (1.00) | TNKS2PARP1KMT2APDE10AMEN1 | |
| SCHEMBL29431542 | 0.80 | PARP1 (0.82) | TNKS2PARP1KMT2APDE10AMEN1 | |
| SCHEMBL5794718 | 0.80 | PARP1 (0.82) | TNKS2PARP1KMT2APDE10AMEN1 | |
| SCHEMBL2260560 | 0.79 | TNKS2 (0.70) | TNKS2PARP1KMT2APDE10AMEN1 | |
| SCHEMBL16404338 | 0.79 | PDE10A (0.84) | TNKS2PARP1KMT2APDE10AMEN1 | |
| SCHEMBL168776 | 0.77 | PARP1 (1.00) | TNKS2PARP1KMT2APDE10AMEN1 | |
| SCHEMBL29900512 | 0.77 | PARP1 (1.00) | TNKS2PARP1KMT2APDE10AMEN1 | |
| SCHEMBL1586541 | 0.76 | PARP1 (0.91) | TNKS2PARP1KMT2APDE10AMEN1 | |
| SCHEMBL14266777 | 0.76 | TNKS2 (0.69) | TNKS2PARP1KMT2APDE10AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100189685-A1 | Antiviral Drugs for Treatment or Prevention of Dengue Infection | SIGA TECHNOLOGIES, INC. | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100189685-A1 | Antiviral Drugs for Treatment or Prevention of Dengue Infection | EIF2AK2, HAVCR2, SNRPE | TNKS2 4740/4885PARP1 4542/4885KMT2A 3347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.