SCHEMBL30176850

SCHEMBL30176850

CCc1nc2ccccc2c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TNKS2 Q9H2K2 2/20 1.00
PARP1 P09874 3/20 0.71
KMT2A Q03164 2/20 0.68
PDE10A Q9Y233 1/20 0.64
MAPT P10636 3/20 0.63
RAB9A P51151 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
GAA P10253 2/20 0.63
NPC1 O15118 1/20 0.63
MEN1 O00255 1/20 0.63
PARP2 Q9UGN5 1/20 0.62
POLB P06746 1/20 0.60
KDM4E B2RXH2 3/20 0.59
LMNA P02545 1/20 0.59
DDAH1 O94760 1/20 0.58
NPSR1 Q6W5P4 1/20 0.57
ALDH1A1 P00352 1/20 0.56
RET P07949 1/20 0.56
KDR P35968 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3826724 1.00 TNKS2 (1.00) TNKS2PARP1KMT2APDE10AMAPT
SCHEMBL5794718 0.86 PARP1 (0.82) TNKS2PARP1KMT2APDE10AMAPT
SCHEMBL29431542 0.86 PARP1 (0.82) TNKS2PARP1KMT2APDE10AMAPT
SCHEMBL16404338 0.85 PDE10A (0.84) TNKS2PARP1KMT2APDE10AMAPT
SCHEMBL168776 0.83 PARP1 (1.00) TNKS2PARP1KMT2APDE10ARAB9A
SCHEMBL29900512 0.83 PARP1 (1.00) TNKS2PARP1KMT2APDE10ARAB9A
SCHEMBL2999541 0.82 TNKS2 (0.69) TNKS2PARP1KMT2APDE10AMAPT
SCHEMBL1586541 0.82 PARP1 (0.91) TNKS2PARP1KMT2APDE10ARAB9A
SCHEMBL14266777 0.82 TNKS2 (0.69) TNKS2PARP1KMT2APDE10AMAPT
SCHEMBL1685046 0.82 TNKS2 (0.70) TNKS2PARP1KMT2APDE10AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462526-A Method for synthesizing quinazolinone compound by catalytic cyclization of titanocene dichloride 陕西师范大学 2025-02-18 CN disclosed
CN-112174899-B Application of light-promoted Minisci C-H alkylation reaction in preparation of alkyl-substituted azacycle 南开大学 2023-01-17 CN disclosed