Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PDE7A | Q13946 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.36 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15689408 | 0.85 | MAPT (0.44) | MAPTMEN1KMT2APDE7APDE7B | |
| SCHEMBL11395682 | 0.83 | MEN1 (0.50) | MAPTMEN1KMT2APDE7AMAPK1 | |
| SCHEMBL8570852 | 0.80 | MAPT (0.47) | MAPTMEN1KMT2ACYP3A4TSHR | |
| SCHEMBL28863243 | 0.78 | MAPT (0.38) | MAPTMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL15689484 | 0.78 | MAPT (0.41) | MAPTMEN1KMT2APDE7AALDH1A1 | |
| SCHEMBL4986190 | 0.75 | MAPT (0.44) | MAPTMAPK1ALDH1A1HTTPOLB | |
| SCHEMBL1713212 | 0.74 | MAPT (1.00) | MAPTMEN1KMT2APDE7ACYP3A4 | |
| SCHEMBL29996298 | 0.73 | ALDH1A1 (0.47) | MAPTMEN1KMT2APDE7ACYP3A4 | |
| SCHEMBL28863204 | 0.73 | MEN1 (0.50) | MAPTMEN1KMT2ATSHRMAPK1 | |
| SCHEMBL15689464 | 0.71 | HSP90AA1 (0.44) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197130-B | Aryl urea derivative and preparation method and application thereof | 安徽医科大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-115197130-A | Aryl urea derivative and preparation method and application thereof | 安徽医科大学 | 2022-10-18 | — | — | CN | disclosed |