SCHEMBL8570852

SCHEMBL8570852

Nc1ccc([N+](=O)[O-])nc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.47
ALDH1A1 P00352 4/20 0.46
POLB P06746 1/20 0.45
RAB9A P51151 1/20 0.41
ALOX15 P16050 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
CYP3A4 P08684 2/20 0.41
TSHR P16473 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA13 Q8N1Q1 1/20 0.41
CA14 Q9ULX7 1/20 0.41
LMNA P02545 1/20 0.40
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29995641 0.80 MAPT (0.59) MAPTALDH1A1POLBCYP3A4TSHR
SCHEMBL29996298 0.80 ALDH1A1 (0.47) MAPTALDH1A1POLBTDP1CYP3A4
SCHEMBL5684639 0.77 ALOX15 (0.47) MAPTALDH1A1POLBRAB9AALOX15
SCHEMBL7089229 0.76 ALDH1A1 (0.45) MAPTALDH1A1POLBRAB9AALOX15
SCHEMBL10936934 0.76 MAPT (0.50) MAPTALDH1A1POLBRAB9ALMNA
SCHEMBL29580092 0.76 MAPT (0.50) MAPTALDH1A1POLBRAB9ALMNA
SCHEMBL18291356 0.75 MAPT (0.41) MAPTPOLBRAB9ATSHRCA12
SCHEMBL17262089 0.74 MAPT (0.47) MAPTALDH1A1POLBRAB9ALMNA
SCHEMBL169463 0.74 MAPT (0.47) MAPTPOLBRAB9ATDP1MEN1
SCHEMBL135841 0.74 MAPT (0.47) MAPTALDH1A1POLBRAB9ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9216869-A None JP disclosed
US-20260001870-A1 INHIBITOR COMPOUNDS Cincera Therapeutics Pty Ltd (AU) 2026-01-01 US disclosed
US-12448371-B2 Inhibitor compounds Cincera Therapeutics Pty Ltd (AU) 2025-10-21 US disclosed
US-20250221979-A1 NOVEL HETEROCYCLIC COMPOUND SHOUYAO HOLDINGS BEIJING CO LTD (CN) 2025-07-10 US disclosed
EP-4501912-A1 NOVEL HETEROCYCLIC COMPOUND Shouyao Holdings (Beijing) Co., Ltd. (CN) 2025-02-05 EP disclosed
CN-114450281-B Inhibitor compounds 辛塞拉治疗私人有限公司 2024-08-16 CN disclosed
CN-118475560-A Novel heterocyclic compound 首药控股(北京)股份有限公司 2024-08-09 CN disclosed
WO-2023185811-A1 NOVEL HETEROCYCLIC COMPOUND 首药控股(北京)股份有限公司 2023-10-05 WO disclosed
CN-116789642-A Tri-aromatic heterocyclic piperazine compound for inducing tumor cell to generate meta death and application thereof 华东师范大学 2023-09-22 CN disclosed
US-20230278965-A1 NOVEL CARBONOHYDRAZONOYL DICYANIDE COMPOUNDS COMPRISING 2 OR MORE ARYL OR HETEROARYL CONNECTED VIA LINKER AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-09-07 US disclosed
EP-0735025-A1 Process for producing aminonitropyridines SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP disclosed
EP-0384364-B1 A composition of nonlinear optical materials and a method for preparing the same MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1994-01-19 EP disclosed
US-5009815-A Composition of nonlinear optical materials and a method for preparing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1991-04-23 US disclosed
EP-0384364-A2 A composition of nonlinear optical materials and a method for preparing the same MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-08-29 EP disclosed
US-4841036-A COLORFAST, HEAT RESISTANCE MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1989-06-20 US disclosed
US-4837309-A IMPROVED COLORFASTNESS AND LIGHTFASTNESS MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1989-06-06 US disclosed
EP-0108570-B1 DISAZO DYESTUFFS FOR CELLULOSE-CONTAINING FIBRES AND PROCESS FOR PREPARING THE DYESTUFF MITSUBISHI KASEI CORPORATION (JP) 1986-10-29 EP disclosed
EP-0121825-B1 MONOAZO DYESTUFFS FOR CELLULOSE-CONTAINING FIBERS MITSUBISHI KASEI CORPORATION (JP) 1986-09-10 EP disclosed
EP-0121825-A1 Monoazo dyestuffs for cellulose-containing fibers MITSUBISHI KASEI CORPORATION (JP) 1984-10-17 EP disclosed
EP-0108570-A2 Disazo dyestuffs for cellulose-containing fibres and process for preparing the dyestuff MITSUBISHI KASEI CORPORATION (JP) 1984-05-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230278965-A1 NOVEL CARBONOHYDRAZONOYL DICYANIDE COMPOUNDS COMPRISING 2 OR MORE ARYL OR HETEROARYL CONNECTED VIA LINKER AND USE THEREOF AADAC, CBR3, MTCL3 MAPT 2830/4885ALDH1A1 1104/4885POLB 4215/4885
US-20250221979-A1 NOVEL HETEROCYCLIC COMPOUND MAPT, MNAT1, MAT2A MAPT 1/4885ALDH1A1 996/4885POLB 2863/4885
US-20260001870-A1 INHIBITOR COMPOUNDS CES1, NCEH1, NR1H2 MAPT 2616/4885ALDH1A1 778/4885POLB 2851/4885
US-12448371-B2 Inhibitor compounds SERPINB1, MMP1, SSB MAPT 2083/4885ALDH1A1 1616/4885POLB 2491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.