Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 11/20 | 0.63 |
| ▸ | CDK9 | P50750 | 11/20 | 0.63 |
| ▸ | CCNA2 | P20248 | 10/20 | 0.63 |
| ▸ | CDK2 | P24941 | 10/20 | 0.63 |
| ▸ | CDK5 | Q00535 | 8/20 | 0.63 |
| ▸ | CDK5R1 | Q15078 | 8/20 | 0.63 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.63 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.60 |
| ▸ | GSK3B | P49841 | 2/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | HTR5A | P47898 | 1/20 | 0.55 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.55 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | STK4 | Q13043 | 1/20 | 0.48 |
| ▸ | STK3 | Q13188 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2993899 | 0.86 | CCNT1 (0.68) | CCNT1CDK9CCNA2CDK2CDK5 | |
| SCHEMBL1839620 | 0.84 | CCNT1 (0.65) | CCNT1CDK9CCNA2CDK2CDK5 | |
| SCHEMBL2986205 | 0.83 | CDK2 (0.67) | CCNT1CDK9CCNA2CDK2CDK5 | |
| SCHEMBL2996921 | 0.83 | CCNT1 (0.64) | CCNT1CDK9CCNA2CDK2CDK5 | |
| SCHEMBL2238967 | 0.82 | CCNT1 (0.65) | CCNT1CDK9CCNA2CDK2CDK5 | |
| SCHEMBL15650217 | 0.81 | ADORA2A (0.57) | CDK5CDK5R1GSK3BDYRK1AMAP3K14 | |
| SCHEMBL2999569 | 0.81 | CCNT1 (0.66) | CCNT1CDK9CCNA2CDK2CDK5 | |
| SCHEMBL1838430 | 0.80 | CCNT1 (0.54) | CCNT1CDK9CCNA2CDK2CDK5 | |
| SCHEMBL1843005 | 0.79 | CCNT1 (0.61) | CCNT1CDK9CCNA2CDK2CDK5 | |
| SCHEMBL1840810 | 0.79 | CCNT1 (0.64) | CCNT1CDK9CCNA2CDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125803-B1 | PYRROLO[2,3-B]PYRIDINE COMPOUNDS, AZAINDOLE COMPOUNDS USED FOR SYNTHESIZING SAID PYRROLO[2,3-B]PYRIDINE COMPOUNDS, METHODS FOR THE PRODUCTION THEREOF, AND USES THEREOF | CENTRE NAT RECH SCIENT (FR) | 2013-04-10 | — | — | EP | disclosed |
| US-20100184790-A1 | PYRROLO[2,3-B]PYRIDINE COMPOUNDS, AZAINDOLE COMPOUNDS USED FOR SYNTHESIZING SAID PYRROLO[2,3-B]PYRIDINE COMPOUNDS, METHODS FOR THE PRODUCTION THEREOF, AND USES THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184790-A1 | PYRROLO[2,3-B]PYRIDINE COMPOUNDS, AZAINDOLE COMPOUNDS USED FOR SYNTHESIZING SAID PYRROLO[2,3-B]PYRIDINE COMPOUNDS, METHODS FOR THE PRODUCTION THEREOF, AND USES THEREOF | BAD, PPOX, CASP3 | CCNT1 1121/4885CDK9 527/4885CCNA2 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.