Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PPID | Q08752 | 1/20 | 0.50 |
| ▸ | CFD | P00746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197745 | 0.82 | PPID (0.52) | SMN1; SMN2PTPN1ALDH1A1KDM4EGAA | |
| SCHEMBL5499261 | 0.80 | ALDH1A1 (0.48) | SMN1; SMN2PTPN1ALDH1A1GAAMAPT | |
| SCHEMBL4188819 | 0.78 | SMN1; SMN2 (0.62) | SMN1; SMN2PTPN1ALDH1A1KDM4EGAA | |
| SCHEMBL714625 | 0.76 | EPHX1 (0.77) | SMN1; SMN2PTPN1ALDH1A1KDM4EGAA | |
| SCHEMBL3614552 | 0.75 | ALDH1A1 (0.52) | SMN1; SMN2PTPN1ALDH1A1KDM4EGAA | |
| SCHEMBL969258 | 0.73 | SMN1; SMN2 (0.67) | SMN1; SMN2PTPN1ALDH1A1GAAMAPT | |
| SCHEMBL6033584 | 0.73 | TP53 (0.75) | SMN1; SMN2PTPN1ALDH1A1KDM4EGAA | |
| SCHEMBL97001 | 0.73 | KMT2A (0.68) | SMN1; SMN2PTPN1ALDH1A1GAAMAPT | |
| SCHEMBL9461525 | 0.73 | MAPT (0.64) | SMN1; SMN2PTPN1ALDH1A1GAAMAPT | |
| SCHEMBL8790488 | 0.73 | SMN1; SMN2 (0.61) | SMN1; SMN2PTPN1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427451-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BioLab Corporation (JP) | 2012-03-14 | — | — | EP | disclosed |
| EP-2303887-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | Prism Biolab Corporation (JP) | 2011-04-06 | — | — | EP | disclosed |