SCHEMBL8790488

SCHEMBL8790488

CONC(=O)NCc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.61
MAPT P10636 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
ALDH1A1 P00352 2/20 0.56
KDM4E B2RXH2 1/20 0.56
GAA P10253 1/20 0.56
ATM Q13315 1/20 0.56
EPHX1 P07099 1/20 0.56
PPID Q08752 1/20 0.55
PTPN1 P18031 2/20 0.55
TP53 P04637 2/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 1/20 0.54
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
TSHR P16473 1/20 0.53
CYP2C19 P33261 1/20 0.53
EPHX2 P34913 1/20 0.53
GLA P06280 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL714625 0.82 EPHX1 (0.77) SMN1; SMN2ALDH1A1KDM4EGAAEPHX1
SCHEMBL27537790 0.80 NPC1 (0.59) SMN1; SMN2MAPTL3MBTL1ALDH1A1KDM4E
SCHEMBL16562080 0.79 NPC1 (0.77) SMN1; SMN2ALDH1A1KDM4EATMPTPN1
SCHEMBL1557310 0.79 EPHX1 (0.53) SMN1; SMN2MAPTL3MBTL1GAAEPHX1
SCHEMBL969258 0.79 SMN1; SMN2 (0.67) SMN1; SMN2MAPTL3MBTL1ALDH1A1GAA
SCHEMBL1720194 0.79 ALDH1A1 (0.67) SMN1; SMN2MAPTL3MBTL1ALDH1A1GAA
SCHEMBL3062841 0.79 EPHX1 (0.61) SMN1; SMN2MAPTKDM4EGAAEPHX1
SCHEMBL6033584 0.78 TP53 (0.75) SMN1; SMN2MAPTALDH1A1KDM4EGAA
SCHEMBL23524610 0.78 ALOX12 (0.68) SMN1; SMN2MAPTALDH1A1KDM4EGAA
SCHEMBL8187605 0.77 TP53 (0.58) SMN1; SMN2MAPTL3MBTL1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805796-A1 CELL ADHESION INHIBITORS BIOGEN, INC. (US) 1997-11-12 EP claimed
WO-1996022966-A1 CELL ADHESION INHIBITORS BIOGEN, INC. (US) 1996-08-01 WO claimed
EP-0805796-A1 CELL ADHESION INHIBITORS BIOGEN, INC. (US) 1997-11-12 EP disclosed
WO-1996022966-A1 CELL ADHESION INHIBITORS BIOGEN, INC. (US) 1996-08-01 WO disclosed