Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.54 |
| ▸ | PRKDC | P78527 | 1/20 | 0.54 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.47 |
| ▸ | CLK2 | P49760 | 3/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.47 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | ROS1 | P08922 | 2/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.47 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.47 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.47 |
| ▸ | LCK | P06239 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27088012 | 1.00 | PIK3CD (0.54) | PIK3CDPRKDCCSNK1A1CLK2CDK5 | |
| SCHEMBL27087999 | 0.85 | SRC (0.45) | PIK3CDPRKDCCSNK1A1CLK2CDK5 | |
| SCHEMBL22215343 | 0.83 | PIK3CD (0.55) | PIK3CDPRKDCCSNK1A1CLK2CDK5 | |
| SCHEMBL868744 | 0.80 | PIK3CD (0.51) | PIK3CDPRKDCCSNK1A1CLK2CDK5 | |
| SCHEMBL16701523 | 0.78 | ADK (0.49) | PIK3CDPRKDCCSNK1A1CLK2CDK5 | |
| SCHEMBL4572201 | 0.77 | RET (0.48) | PIK3CDPRKDCCSNK1A1CLK2CDK5 | |
| SCHEMBL868521 | 0.77 | DYRK3 (0.51) | PIK3CDPRKDCCSNK1A1CLK2CDK5 | |
| SCHEMBL24096485 | 0.76 | PIK3CG (0.54) | PIK3CDPRKDCCSNK1A1CLK2CDK5 | |
| SCHEMBL19283009 | 0.76 | ADK (0.49) | PIK3CDPRKDCCSNK1A1CLK2CDK5 | |
| SCHEMBL17936088 | 0.76 | MAPK1 (0.47) | PIK3CDPRKDCCSNK1A1CLK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320127-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022216680-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-13 | — | — | WO | disclosed |