Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.55 |
| ▸ | PRKDC | P78527 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 4/20 | 0.38 |
| ▸ | YES1 | P07947 | 3/20 | 0.38 |
| ▸ | FGR | P09769 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27088012 | 0.83 | PIK3CD (0.54) | PIK3CDPRKDCMAPK1KDM4ECYP1A2 | |
| SCHEMBL29998401 | 0.83 | PIK3CD (0.54) | PIK3CDPRKDCMAPK1KDM4ECYP1A2 | |
| SCHEMBL10261498 | 0.80 | PIK3CD (0.53) | PIK3CDPRKDCMAPK1KDM4ECYP1A2 | |
| SCHEMBL29678005 | 0.77 | PIK3CD (0.74) | PIK3CDPRKDCMAPK1KDM4ECYP1A2 | |
| SCHEMBL10261070 | 0.76 | SRC (0.52) | PIK3CDPRKDCMAPK1KDM4ECYP1A2 | |
| SCHEMBL13019686 | 0.76 | PIK3CD (0.68) | PIK3CDPRKDCMAPK1KDM4ECYP1A2 | |
| SCHEMBL21028946 | 0.75 | PIK3CD (0.55) | PIK3CDPRKDCMAPK1KDM4ECYP1A2 | |
| SCHEMBL26148251 | 0.75 | MAPK1 (0.42) | PIK3CDPRKDCMAPK1KDM4ECYP1A2 | |
| SCHEMBL10260251 | 0.74 | PIK3CD (0.52) | PIK3CDPRKDCSRCLRRK2KDR | |
| SCHEMBL25113285 | 0.74 | RET (0.43) | PIK3CDPRKDCMAPK1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11433065-B2 | Certain chemical entities, compositions and methods | INTELLIKINE LLC (US) | 2022-09-06 | — | — | US | disclosed |
| US-20200222384-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE, INC. | 2020-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200222384-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | PIK3CA, AKT3, PIK3C2A | PIK3CD 7/4885PRKDC 64/4885MAPK1 436/4885 |
| US-11433065-B2 | Certain chemical entities, compositions and methods | PIK3CA, AKT3, PIK3C2A | PIK3CD 7/4885PRKDC 64/4885MAPK1 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.