Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GLA | P06280 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.54 |
| ▸ | PI4KA | P42356 | 1/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 7/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524111 | 0.90 | KDM4E (0.61) | KDM4ESMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL12408902 | 0.88 | KDM4E (0.70) | KDM4ESMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL19733171 | 0.85 | RAB9A (0.66) | KDM4ESMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL2380254 | 0.83 | RAB9A (0.68) | KDM4ESMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL2995582 | 0.81 | MAPT (0.67) | KDM4ESMN1; SMN2LMNAMAPTGAA | |
| SCHEMBL29939237 | 0.81 | MAPT (0.79) | KDM4ESMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL27001616 | 0.81 | MAPT (0.79) | KDM4ESMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL31319825 | 0.81 | MAPT (0.79) | KDM4ESMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL30727497 | 0.81 | APP (0.62) | KDM4ESMN1; SMN2LMNANFKB1NFKB2 | |
| SCHEMBL13241670 | 0.79 | KDM4E (0.59) | KDM4ESMN1; SMN2LMNANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190994-A1 | THIAZOLE SYSTEM ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME | LEE MI AE | 2010-07-29 | — | — | US | disclosed |
| EP-2129738-A1 | THIAZOLE SYSTEM ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME | Gracel Display Inc. (KR) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008117976-A1 | THIAZOLE SYSTEM ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME | GRACEL DISPLAY INC. (KR) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190994-A1 | THIAZOLE SYSTEM ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE USING THE SAME | OCIAD1, OCIAD2, PPARD | KDM4E 3995/4885SMN1; SMN2 4131/4885LMNA 3917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.