Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.45 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2999911 | 1.00 | ALDH1A1 (0.55) | ALDH1A1HTTCYP1A2CYP2D6KDM4E | |
| SCHEMBL6997673 | 0.81 | HTT (0.67) | ALDH1A1HTTCYP1A2CYP2D6PFKFB3 | |
| SCHEMBL6997670 | 0.81 | HTT (0.67) | ALDH1A1HTTCYP1A2CYP2D6PFKFB3 | |
| SCHEMBL14305656 | 0.81 | HTT (0.58) | ALDH1A1HTTCYP1A2CYP2D6PFKFB3 | |
| SCHEMBL14313397 | 0.77 | HTT (0.53) | ALDH1A1HTTCYP1A2CYP2D6PFKFB3 | |
| SCHEMBL14305657 | 0.77 | HTT (0.53) | ALDH1A1HTTCYP1A2CYP2D6KDM4E | |
| SCHEMBL14313402 | 0.77 | HTT (0.53) | ALDH1A1HTTCYP1A2CYP2D6PFKFB3 | |
| SCHEMBL14303900 | 0.75 | NPC1 (0.77) | ALDH1A1HTTCYP1A2KDM4ECYP3A4 | |
| SCHEMBL14305653 | 0.74 | HTT (0.54) | ALDH1A1HTTCYP1A2CYP2D6CYP3A4 | |
| SCHEMBL27687985 | 0.74 | HTT (0.63) | ALDH1A1HTTCYP1A2CYP2D6PFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184811-A1 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | BRIDGE BIORESEARCH RIGHTS (JERSEY) LIMITED (GB) | 2010-07-22 | — | — | US | disclosed |
| EP-2068873-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | Pharma 2100 (DK) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008031440-A2 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | PHARMA 2100 (DK) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184811-A1 | ISONIAZID MEDIATED HEALING OF WOUNDS AND ULCERS | ODC1, OTC, ACACB | ALDH1A1 302/4885HTT 3833/4885CYP1A2 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.