Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597293 | 1.00 | KDM4E (0.52) | KDM4EALOX5HDAC3HDAC4HDAC1 | |
| SCHEMBL6369134 | 0.86 | KDM4E (0.42) | KDM4EALOX5HDAC3HDAC4HDAC1 | |
| SCHEMBL9101781 | 0.83 | KDM4E (0.52) | KDM4EALOX5HDAC3HDAC4HDAC1 | |
| SCHEMBL9101771 | 0.83 | KDM4E (0.52) | KDM4EALOX5HDAC3HDAC4HDAC1 | |
| SCHEMBL6369131 | 0.82 | KDM4E (0.44) | KDM4EALOX5HDAC3HDAC4HDAC1 | |
| SCHEMBL6369128 | 0.82 | KDM4E (0.44) | KDM4EALOX5HDAC3HDAC4HDAC1 | |
| SCHEMBL14898033 | 0.75 | KDM4E (0.50) | KDM4EALOX5HDAC3HDAC4HDAC1 | |
| SCHEMBL29999634 | 0.74 | KDM4E (0.49) | KDM4EALOX5HDAC3HDAC4HDAC1 | |
| SCHEMBL16196756 | 0.72 | KDM4E (0.41) | KDM4EALOX5HDAC3HDAC4HDAC1 | |
| SCHEMBL2717774 | 0.72 | KDM4E (0.69) | KDM4EALOX5HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002038107-A2 | STAT MODULATORS | TULARIK INC. (US) | 2002-05-16 | — | — | WO | disclosed |