Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30873380 | 0.86 | LMNA (0.43) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL15464283 | 0.86 | LMNA (0.43) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL29999653 | 0.81 | LMNA (0.41) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL26694776 | 0.81 | LMNA (0.41) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL16194467 | 0.81 | LMNA (0.41) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL31187651 | 0.79 | LMNA (0.40) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL28903971 | 0.78 | NPC1 (0.51) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL31256425 | 0.78 | VNN1 (0.39) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL23974786 | 0.77 | PIK3CD (0.42) | LMNAMAPTCYP1A2CYP2D6TSHR | |
| SCHEMBL30708392 | 0.77 | LMNA (0.39) | LMNAMAPTCYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320132-A1 | OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER | Genentech, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022216762-A1 | OXAZEPINE COMPOUNDS AND USES THEREOF IN THE TREATMENT OF CANCER | GENENTECH, INC. (US) | 2022-10-13 | — | — | WO | disclosed |