Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25204150 | 0.88 | KDM4E (0.73) | TNKSKDM4EALDH1A1HSD17B10CYP2C19 | |
| SCHEMBL30398533 | 0.88 | TNKS (0.69) | TNKSKDM4EALDH1A1HSD17B10CYP2C19 | |
| SCHEMBL30000213 | 0.86 | KDM4E (0.67) | TNKSKDM4EALDH1A1HSD17B10CYP2C19 | |
| SCHEMBL30000857 | 0.86 | TNKS (0.70) | TNKSKDM4EALDH1A1HSD17B10CYP2C19 | |
| SCHEMBL30000112 | 0.85 | TNKS (0.69) | TNKSKDM4EALDH1A1HSD17B10CYP2C19 | |
| SCHEMBL30000307 | 0.85 | TNKS (0.69) | TNKSKDM4EALDH1A1HSD17B10CYP2C19 | |
| SCHEMBL8934614 | 0.84 | KDM4E (0.74) | TNKSKDM4EALDH1A1HSD17B10CYP2C19 | |
| SCHEMBL31552889 | 0.82 | ALDH1A1 (0.76) | TNKSKDM4EALDH1A1HSD17B10CYP2C19 | |
| SCHEMBL30000198 | 0.82 | TNKS (1.00) | TNKSKDM4EALDH1A1HSD17B10CYP2C19 | |
| SCHEMBL10885932 | 0.81 | TNKS (0.71) | TNKSKDM4EALDH1A1HSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255765-A1 | NOVEL FLUORINE-SUBSTITUTED FLAVONOID DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ALLERGIC DISEASES, COMPRISING SAME | 주식회사 에즈큐리스 | 2022-12-08 | — | — | WO | claimed |
| WO-2022255765-A1 | NOVEL FLUORINE-SUBSTITUTED FLAVONOID DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ALLERGIC DISEASES, COMPRISING SAME | 주식회사 에즈큐리스 | 2022-12-08 | — | — | WO | disclosed |