Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.74 |
| ▸ | HPGD | P15428 | 5/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.74 |
| ▸ | TP53 | P04637 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.71 |
| ▸ | FYN | P06241 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | PPARG | P37231 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.65 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.65 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31552889 | 0.87 | ALDH1A1 (0.76) | KDM4ECYP3A4CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL8934505 | 0.86 | CYP1A1 (0.69) | KDM4ECYP3A4CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL10068612 | 0.86 | CSNK2A2 (0.69) | KDM4ECYP3A4CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL4650049 | 0.85 | KDM4E (1.00) | KDM4ECYP3A4CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL31527819 | 0.85 | KDM4E (1.00) | KDM4ECYP3A4CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL25204150 | 0.85 | KDM4E (0.73) | KDM4ECYP3A4CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL29999985 | 0.84 | TNKS (0.69) | KDM4ECYP3A4CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL30266579 | 0.83 | CYP3A4 (1.00) | KDM4ECYP3A4CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL312254 | 0.83 | CYP3A4 (1.00) | KDM4ECYP3A4CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL8934506 | 0.82 | TUBB4A (0.79) | KDM4ECYP3A4CYP2C19ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |