Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.50 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.49 |
| ▸ | TUBB | P07437 | 3/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.49 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.49 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.49 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.49 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.49 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.49 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.49 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.49 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.49 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.49 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.49 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28597096 | 1.00 | KRAS (0.50) | KRASTNFRSF1ATUBB4ATUBBTUBA3C | |
| SCHEMBL30000566 | 1.00 | KRAS (0.50) | KRASTNFRSF1ATUBB4ATUBBTUBA3C | |
| SCHEMBL28610978 | 0.86 | TNFRSF1A (0.53) | KRASTNFRSF1ATUBB4ATUBBTUBA3C | |
| SCHEMBL28601785 | 0.82 | ABCG2 (0.53) | TNFRSF1AMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL28596998 | 0.80 | ALDH1A1 (0.58) | TNFRSF1AMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL30000594 | 0.78 | LMNA (0.57) | MAPTALDH1A1LMNANPSR1RAB9A | |
| SCHEMBL28602254 | 0.77 | ALDH1A1 (0.54) | TNFRSF1AMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL28919499 | 0.76 | TNFRSF1A (0.53) | TNFRSF1AMAPTALDH1A1LMNANPSR1 | |
| SCHEMBL12484518 | 0.69 | TNFRSF1A (1.00) | KRASTNFRSF1ATUBB4ATUBBTUBA3C | |
| SCHEMBL12484514 | 0.69 | TNFRSF1A (1.00) | KRASTNFRSF1ATUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072501-B | 1-phenyl-3- (pyrazol-4-yl) prop-2-ene-1-one derivative and preparation method and medical application thereof | 武汉科技大学 | 2022-10-14 | — | — | CN | claimed |
| CN-113072501-B | 1-phenyl-3- (pyrazol-4-yl) prop-2-ene-1-one derivative and preparation method and medical application thereof | 武汉科技大学 | 2022-10-14 | — | — | CN | disclosed |