Neoplanocin A

Neoplanocin A

SCHEMBL30001474

Nc1ncnc2c1ncn2[C@H]1C=C(CO)[C@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHCY P23526 12/20 1.00
EZH2 Q15910 1/20 0.66
AHCYL1 O43865 1/20 0.65
ADORA3 P0DMS8 3/20 0.56
DPP4 P27487 1/20 0.56
MEN1 O00255 1/20 0.56
SLC28A1 O00337 1/20 0.56
MAP3K7 O43318 1/20 0.56
SLC28A2 O43868 1/20 0.56
GAPDH P04406 1/20 0.56
MAPK1 P28482 1/20 0.56
ADORA2A P29274 1/20 0.56
ADORA2B P29275 1/20 0.56
ADORA1 P30542 1/20 0.56
STAT6 P42226 1/20 0.56
PI4KA P42356 1/20 0.56
KMT2A Q03164 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
PI4K2B Q8TCG2 1/20 0.56
DOT1L Q8TEK3 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Neoplanocin A SCHEMBL863873 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
Neoplanocin A SCHEMBL12174034 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
Neoplanocin A SCHEMBL30543748 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
Neoplanocin A SCHEMBL29708080 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
Neoplanocin A SCHEMBL17117192 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
Neoplanocin A SCHEMBL12157269 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
Neoplanocin A SCHEMBL10469277 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
Neoplanocin A SCHEMBL10576831 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
SCHEMBL15396253 0.90 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
SCHEMBL29711226 0.90 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4602148-A1 METHODS FOR CHEMICAL REPROGRAMMING AND PLURIPOTENT STEM CELLS Peking University (CN) 2025-08-20 EP disclosed
WO-2024078119-A1 METHODS FOR CHEMICAL REPROGRAMMING AND PLURIPOTENT STEM CELLS PEKING UNIVERSITY (CN) 2024-04-18 WO disclosed
WO-2024078118-A1 CHEMICAL REPROGRAMMING AND PLURIPOTENT STEM CELLS PEKING UNIVERSITY (CN) 2024-04-18 WO disclosed
EP-4320223-A1 CHEMICAL REPROGRAMMING OF HUMAN SOMATIC CELLS INTO PLURIPOTENT CELLS Peking University (CN) 2024-02-14 EP disclosed
WO-2022213731-A1 CHEMICAL REPROGRAMMING OF HUMAN SOMATIC CELLS INTO PLURIPOTENT CELLS PEKING UNIVERSITY (CN) 2022-10-13 WO disclosed