Neoplanocin A

Neoplanocin A

SCHEMBL10469277

Nc1ncnc2c1ncn2[C@@H]1C=C(CO)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHCY P23526 12/20 1.00
EZH2 Q15910 1/20 0.66
AHCYL1 O43865 1/20 0.65
ADORA3 P0DMS8 3/20 0.56
DPP4 P27487 1/20 0.56
MEN1 O00255 1/20 0.56
SLC28A1 O00337 1/20 0.56
MAP3K7 O43318 1/20 0.56
SLC28A2 O43868 1/20 0.56
GAPDH P04406 1/20 0.56
MAPK1 P28482 1/20 0.56
ADORA2A P29274 1/20 0.56
ADORA2B P29275 1/20 0.56
ADORA1 P30542 1/20 0.56
STAT6 P42226 1/20 0.56
PI4KA P42356 1/20 0.56
KMT2A Q03164 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
PI4K2B Q8TCG2 1/20 0.56
DOT1L Q8TEK3 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Neoplanocin A SCHEMBL863873 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
Neoplanocin A SCHEMBL30001474 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
Neoplanocin A SCHEMBL12174034 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
Neoplanocin A SCHEMBL30543748 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
Neoplanocin A SCHEMBL29708080 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
Neoplanocin A SCHEMBL17117192 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
Neoplanocin A SCHEMBL12157269 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
Neoplanocin A SCHEMBL10576831 1.00 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
SCHEMBL15396253 0.90 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4
SCHEMBL29711226 0.90 AHCY (1.00) AHCYEZH2AHCYL1ADORA3DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340848-A1 METHODS FOR CHEMICAL REPROGRAMMING AND PLURIPOTENT STEM CELLS PEKING UNIVERSITY (CN) 2025-11-06 US claimed
CN-120127338-A Diaphragm modified material and preparation method thereof, modified diaphragm and preparation method thereof 西南石油大学 2025-06-10 CN claimed
EP-3019596-B1 COMPOSITIONS AND METHODS FOR REPROGRAMING NON- PLURIPOTENT CELLS INTO PLURIPOTENT STEM CELLS HONG GUAN LTD (CN) 2023-07-05 EP claimed
WO-2022160323-A1 APPLICATION OF NUCLEOSIDE ANALOGUE IN PREPARATION OF DRUGS FOR PREVENTING OR TREATING GASTROINTESTINAL DISEASES 兰州大学 2022-08-04 WO claimed
CN-114533739-A Application of nucleoside analogue in preparing medicine for preventing or treating gastrointestinal tract diseases 兰州大学 2022-05-27 CN claimed
US-12590288-B2 Method of treating an inflammatory disease by administering an agent which binds a surface receptor on a tuft cell that induces an ILC class 2 inflammatory response THE BROAD INSTITUTE, INC. (US) 2026-03-31 US disclosed
US-12466849-B2 Anti-viral and anti-tumoral compounds YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2025-11-11 US disclosed
US-20250340848-A1 METHODS FOR CHEMICAL REPROGRAMMING AND PLURIPOTENT STEM CELLS PEKING UNIVERSITY (CN) 2025-11-06 US disclosed
US-20250326725-A1 PI4-Kinase Inhibitors and Methods of Using the Same UNIV LELAND STANFORD JUNIOR (US) 2025-10-23 US disclosed
US-12415788-B2 PI4-kinase inhibitors and methods of using the same THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-09-16 US disclosed
EP-4602148-A1 METHODS FOR CHEMICAL REPROGRAMMING AND PLURIPOTENT STEM CELLS Peking University (CN) 2025-08-20 EP disclosed
CN-120127338-A Diaphragm modified material and preparation method thereof, modified diaphragm and preparation method thereof 西南石油大学 2025-06-10 CN disclosed
US-20150291640-A1 PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2015-10-15 US disclosed
US-20150291640-A1 PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2015-10-15 US disclosed
WO-2014204856-A1 FATTY ACID ANTICANCER DERIVATIVES AND THEIR USES CATABASIS PHARMACEUTICALS, INC. (US) 2014-12-24 WO disclosed
WO-2014079903-A1 PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS UNIVERSITY COLLEGE CORK (IE) 2014-05-30 WO disclosed
US-20110237606-A1 3-Deazaneplanocin Derivatives AGENCY OF SCIENCE, TECHNOLOGY AND RESEARCH 2011-09-29 US disclosed
US-20110237606-A1 3-Deazaneplanocin Derivatives AGENCY OF SCIENCE, TECHNOLOGY AND RESEARCH 2011-09-29 US disclosed
WO-2010036213-A1 3-DEAZANEPLANOCIN DERIVATIVES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-04-01 WO disclosed
US-4968690-A 3-deazaneplanocin, intermediates for it, and antiviral composition and method of treatment using it UNITED STATES GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH AND HUMAN SERVICES (US) 1990-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250326725-A1 PI4-Kinase Inhibitors and Methods of Using the Same PI4KB, PI4KA, PI4K2A AHCY 1340/4885EZH2 3432/4885AHCYL1 960/4885
US-12466849-B2 Anti-viral and anti-tumoral compounds EIF2AK2, NSUN2, SARS1 AHCY 3018/4885EZH2 463/4885AHCYL1 2373/4885
US-12415788-B2 PI4-kinase inhibitors and methods of using the same PI4KB, PI4KA, PI4K2A AHCY 1340/4885EZH2 3432/4885AHCYL1 960/4885
US-12590288-B2 Method of treating an inflammatory disease by administering an agent which binds a surface receptor on a tuft cell that induces an ILC class 2 inflammatory response GPR3, GALR3, NR4A3 AHCY 3973/4885EZH2 1721/4885AHCYL1 2763/4885
US-20110237606-A1 3-Deazaneplanocin Derivatives EZH2, SUZ12, DAZAP1 AHCY 4001/4885EZH2 1/4885AHCYL1 3115/4885
US-20150291640-A1 PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS ENTPD5, PNP, MTAP AHCY 4360/4885EZH2 2574/4885AHCYL1 4593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.