Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29183039 | 0.81 | FAAH (0.41) | FAAH | |
| SCHEMBL30907320 | 0.76 | TSHR (0.42) | FAAH | |
| SCHEMBL179570 | 0.75 | — | — | |
| SCHEMBL28425194 | 0.74 | FAAH (0.37) | FAAH | |
| SCHEMBL28517385 | 0.74 | FAAH (0.37) | FAAH | |
| SCHEMBL27173068 | 0.74 | FAAH (0.37) | FAAH | |
| SCHEMBL23202631 | 0.73 | — | — | |
| SCHEMBL18780480 | 0.73 | — | — | |
| SCHEMBL16945372 | 0.71 | — | — | |
| SCHEMBL13080643 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4347032-A1 | SUBSTITUTED TETRAHYDROFURAN-2-CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | Vertex Pharmaceuticals Incorporated (US) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022256702-A1 | SUBSTITUTED TETRAHYDROFURAN-2-CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-12-08 | — | — | WO | disclosed |