Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 8/20 | 0.32 |
| ▸ | PKLR | P30613 | 6/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | USP9X | Q93008 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892390 | 1.00 | KDM4E (0.35) | KDM4EACLYPKMPKLRERN1 | |
| SCHEMBL28581319 | 0.78 | KDM4E (0.40) | KDM4EACLYPKMPKLRERN1 | |
| SCHEMBL1058342 | 0.73 | ALDH1A1 (0.43) | KDM4EACLYERN1CTNNB1WNT3A | |
| SCHEMBL18106671 | 0.70 | ERN1 (0.36) | PKMERN1TDP1 | |
| SCHEMBL909951 | 0.69 | LMNA (0.42) | PKMPKLRERN1TDP1ALDH1A1 | |
| SCHEMBL441131 | 0.69 | CA1 (0.44) | ERN1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL28892613 | 0.68 | — | — | |
| SCHEMBL28892511 | 0.68 | CTNNB1 (0.31) | CTNNB1WNT3A | |
| SCHEMBL30002686 | 0.68 | CTNNB1 (0.31) | CTNNB1WNT3A | |
| SCHEMBL30002413 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |