Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | GNRHR | P30968 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892774 | 1.00 | KIT (0.35) | KITERBB2EPHA2KDRPIK3CG | |
| SCHEMBL30002766 | 0.90 | EPHA2 (0.37) | KITERBB2EPHA2KDRNPC1 | |
| SCHEMBL28892550 | 0.90 | EPHA2 (0.37) | KITERBB2EPHA2KDRNPC1 | |
| SCHEMBL28892349 | 0.83 | KIT (0.34) | KITEPHA2KDRPIK3CGALDH1A1 | |
| SCHEMBL30002757 | 0.83 | KIT (0.34) | KITEPHA2KDRPIK3CGALDH1A1 | |
| SCHEMBL30003289 | 0.81 | GAA (0.35) | ALDH1A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28892418 | 0.81 | KIT (0.37) | KITERBB2EPHA2KDRPIK3CG | |
| SCHEMBL30003338 | 0.81 | KIT (0.37) | KITERBB2EPHA2KDRPIK3CG | |
| SCHEMBL30002017 | 0.80 | NPC1 (0.35) | KITERBB2EPHA2KDRNPC1 | |
| SCHEMBL28892399 | 0.79 | KIT (0.39) | KITERBB2EPHA2KDRPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |