Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 6/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | GNRHR | P30968 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | KIF5B | P33176 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892418 | 1.00 | KIT (0.37) | KITP2RX7KDRERBB2EPHA2 | |
| SCHEMBL30002519 | 0.83 | DHFR (0.37) | KITKDREPHA2PIK3CGCSF1R | |
| SCHEMBL29211328 | 0.83 | DHFR (0.37) | KITKDREPHA2PIK3CGCSF1R | |
| SCHEMBL28892725 | 0.81 | ALDH1A1 (0.36) | P2RX7ALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL30002458 | 0.81 | ALDH1A1 (0.36) | P2RX7ALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL30002067 | 0.81 | KIT (0.35) | KITKDRERBB2EPHA2PIK3CG | |
| SCHEMBL28892774 | 0.81 | KIT (0.35) | KITKDRERBB2EPHA2PIK3CG | |
| SCHEMBL28892739 | 0.79 | KIT (0.35) | KITRETCSF1RALDH1A1MEN1 | |
| SCHEMBL30002396 | 0.79 | KIT (0.35) | KITRETCSF1RALDH1A1MEN1 | |
| SCHEMBL30003339 | 0.79 | KIT (0.39) | KITKDRERBB2EPHA2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |