Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064597 | 1.00 | HDAC3 (0.49) | HDAC3HDAC1HDAC2HDAC6FFAR1 | |
| SCHEMBL31321848 | 0.86 | PDCD1 (0.46) | HDAC3HDAC1HDAC2HDAC6FFAR1 | |
| SCHEMBL6498758 | 0.86 | PDCD1 (0.46) | HDAC3HDAC1HDAC2HDAC6FFAR1 | |
| SCHEMBL3207839 | 0.84 | MEN1 (0.46) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL9886157 | 0.84 | HDAC3 (0.50) | HDAC3HDAC1HDAC2HDAC6FFAR1 | |
| SCHEMBL8936738 | 0.83 | KDM4E (0.42) | HDAC3HDAC1HDAC2HDAC6FFAR1 | |
| SCHEMBL16959556 | 0.83 | CYP1A2 (0.55) | PTGDR2L3MBTL1MAPTPPARDPPARA | |
| SCHEMBL40098 | 0.82 | HDAC3 (0.46) | HDAC3HDAC1HDAC2HDAC6FFAR1 | |
| SCHEMBL40119 | 0.82 | L3MBTL1 (0.47) | HDAC3HDAC1HDAC2HDAC6FFAR1 | |
| SCHEMBL28465158 | 0.82 | HDAC3 (0.46) | HDAC3HDAC1HDAC2HDAC6FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |