Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959556 | 0.84 | CYP1A2 (0.55) | KMT2APPARGPPARDPPARAPTGDR2 | |
| SCHEMBL30002156 | 0.83 | HDAC3 (0.49) | PPARDPPARAPTGDR2HDAC3HDAC1 | |
| SCHEMBL4064597 | 0.83 | HDAC3 (0.49) | PPARDPPARAPTGDR2HDAC3HDAC1 | |
| SCHEMBL4870587 | 0.81 | KDM4E (0.44) | KDM4EHTTKMT2APTGDR2HPGD | |
| SCHEMBL2116117 | 0.79 | MAPK1 (0.41) | KDM4EKMT2APTGDR2HPGDALDH1A1 | |
| SCHEMBL29953675 | 0.78 | KDM4E (0.42) | KDM4EHTTKMT2APTGDR2HDAC3 | |
| SCHEMBL16400097 | 0.77 | PTGDR2 (0.66) | PPARGPPARDPPARAPTGDR2MAPT | |
| SCHEMBL16961613 | 0.76 | RXRA (0.40) | PTGDR2CYP1A2CYP2C9CYP2C19HTR2A | |
| SCHEMBL6211474 | 0.76 | RXRA (0.55) | PTGDR2SLC6A4MRGPRX4 | |
| SCHEMBL8712221 | 0.76 | PTGDR2 (0.59) | KDM4EHTTKMT2APTGDR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |