Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.74 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.74 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.70 |
| ▸ | HTR2A | P28223 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.70 |
| ▸ | HTR1A | P08908 | 2/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.70 |
| ▸ | HTR2B | P41595 | 3/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.68 |
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HTR2C | P28335 | 2/20 | 0.68 |
| ▸ | SCN1A | P35498 | 2/20 | 0.68 |
| ▸ | HTR6 | P50406 | 2/20 | 0.68 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.68 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Moprolol SCHEMBL30910938 | 1.00 | ADRB2 (0.74) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| Levomoprolol SCHEMBL80725 | 1.00 | ADRB2 (0.74) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| Moprolol SCHEMBL80724 | 1.00 | ADRB2 (0.74) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| Moprolol SCHEMBL9119947 | 0.98 | ADRB2 (0.72) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| Levomoprolol SCHEMBL9120389 | 0.98 | ADRB2 (0.72) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| Moprolol SCHEMBL1649455 | 0.97 | ADRB2 (0.70) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| SCHEMBL11868102 | 0.94 | ADRB2 (0.82) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11874444 | 0.92 | ADRB2 (0.80) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| SCHEMBL10735720 | 0.89 | ADRB2 (0.76) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| SCHEMBL10743558 | 0.88 | CYP1A2 (0.60) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110831584-B | Targeted drug rescue with novel compositions, combinations and methods thereof | 埃克塞瓦有限责任公司 | 2023-03-10 | — | — | CN | disclosed |
| US-11478467-B2 | Targeted drug rescue with novel compositions, combinations, and methods thereof | Exciva GmbH (DE) | 2022-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11478467-B2 | Targeted drug rescue with novel compositions, combinations, and methods thereof | HTR2A, HTR2C, CYP3A43 | ADRB2 61/4885ADRB1 129/4885ADRB3 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.