Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.74 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.74 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.70 |
| ▸ | HTR2A | P28223 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.70 |
| ▸ | HTR1A | P08908 | 2/20 | 0.70 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.70 |
| ▸ | HTR2B | P41595 | 3/20 | 0.68 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.68 |
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HTR2C | P28335 | 2/20 | 0.68 |
| ▸ | SCN1A | P35498 | 2/20 | 0.68 |
| ▸ | HTR6 | P50406 | 2/20 | 0.68 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.68 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Moprolol SCHEMBL30910938 | 1.00 | ADRB2 (0.74) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| Levomoprolol SCHEMBL80725 | 1.00 | ADRB2 (0.74) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| Moprolol SCHEMBL30002163 | 1.00 | ADRB2 (0.74) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| Moprolol SCHEMBL9119947 | 0.98 | ADRB2 (0.72) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| Levomoprolol SCHEMBL9120389 | 0.98 | ADRB2 (0.72) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| Moprolol SCHEMBL1649455 | 0.97 | ADRB2 (0.70) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| SCHEMBL11868102 | 0.94 | ADRB2 (0.82) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11874444 | 0.92 | ADRB2 (0.80) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| SCHEMBL10735720 | 0.89 | ADRB2 (0.76) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| SCHEMBL10743558 | 0.88 | CYP1A2 (0.60) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2699 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119233997-A | Tetrahedral antibodies | 生物分子控股有限责任公司 | 2024-12-31 | — | — | CN | claimed |
| EP-4463485-A2 | TETRAHEDRAL ANTIBODIES | Biomolecular Holdings LLC (US) | 2024-11-20 | — | — | EP | claimed |
| CN-118384290-A | Hybrid immunoglobulins containing non-peptide linkages | 生物分子控股有限责任公司 | 2024-07-26 | — | — | CN | claimed |
| WO-2024133913-A2 | SEMIFLUORINATED ALKANE COMPOSITIONS COMPRISING HYOSCYAMINE | NOVALIQ GMBH (DE) | 2024-06-27 | — | — | WO | claimed |
| WO-2023183932-A2 | MONOBODIES BINDING TO INTERCELLULAR ADHESION MOLECULE 2 (ICAM-2) | NEW YORK UNIVERSITY (US) | 2023-09-28 | — | — | WO | claimed |
| WO-2023137387-A2 | TETRAHEDRAL ANTIBODIES | BIOMOLECULAR HOLDINGS LLC (US) | 2023-07-20 | — | — | WO | claimed |
| WO-2023137373-A1 | TETRAHEDRAL ANTIBODIES | BIOMOLECULAR HOLDINGS LLC (US) | 2023-07-20 | — | — | WO | claimed |
| US-20230220115-A1 | TETRAHEDRAL ANTIBODIES | BIOMOLECULAR HOLDINGS LLC (US) | 2023-07-13 | — | — | US | claimed |
| US-20230220116-A1 | TETRAHEDRAL ANTIBODIES | BIOMOLECULAR HOLDINGS LLC (US) | 2023-07-13 | — | — | US | claimed |
| EP-4178615-A1 | TETRAHEDRAL ANTIBODIES | Biomolecular Holdings LLC (US) | 2023-05-17 | — | — | EP | claimed |
| EP-0157409-A2 | Renin inhibitors containing 2-substituted statine | MERCK & CO. INC. (US) | 1985-10-09 | — | — | EP | claimed |
| EP-0156318-A2 | C-terminal amide cyclic renin inhibitors containing peptide isosteres | MERCK & CO. INC. (US) | 1985-10-02 | — | — | EP | claimed |
| EP-0156322-A2 | Renin inhibitors containing peptide isosteres | MERCK & CO. INC. (US) | 1985-10-02 | — | — | EP | claimed |
| EP-0129189-A2 | Renin inhibitors containing a C-terminal amide cycle and compositions and combinations containing the same | MERCK & CO. INC. (US) | 1984-12-27 | — | — | EP | claimed |
| EP-0015418-B1 | PROCESS FOR THE SEPARATION OF THE TWO OPTICAL ISOMERS OF 1-(O-METHOXYPHENOXY)-3-ISOPROPYLAMINO-PROPAN-2-OL, OPTICAL ISOMERS OBTAINED THEREBY AND PHARMACEUTICAL COMPOSITIONS OF THE LEVOROTATORY ANTIPODE THEREOF | SIMES S.p.A. Società Italiana Medicinali e Sintetici (IT) | 1982-07-21 | — | — | EP | claimed |
| US-4303637-A | Medication indicated for ocular hypertension | ALZA CORPORATION (US) | 1981-12-01 | — | — | US | claimed |
| EP-0037622-A2 | Drug delivery insert for controlled ocular therapy | ALZA CORPORATION (US) | 1981-10-14 | — | — | EP | claimed |
| US-4281654-A | Drug delivery system for controlled ocular therapy | ALZA CORPORATION (US) | 1981-08-04 | — | — | US | claimed |
| EP-0015418-A1 | Process for the separation of the two optical isomers of 1-(o-methoxyphenoxy)-3-isopropylamino-propan-2-ol, optical isomers obtained thereby and pharmaceutical compositions of the levorotatory antipode thereof | SIMES S.p.A. Società Italiana Medicinali e Sintetici (IT) | 1980-09-17 | — | — | EP | claimed |
| US-4190654-A | Pharmaceutical composition comprising anxiolytic drugs and beta-adrenergic receptor blocking agents | Simes Societa Italiana Medicinali e Sintatici S.p.A. (IT) | 1980-02-26 | — | — | US | claimed |