SCHEMBL3000236

SCHEMBL3000236

O=C(/C=C/c1ccc(CCc2ccc(N3C(=O)C=CC3=O)cc2)cc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.54
KMT2A Q03164 6/20 0.54
ALDH1A1 P00352 5/20 0.54
MEN1 O00255 4/20 0.54
NPSR1 Q6W5P4 1/20 0.54
MAOB P27338 4/20 0.53
BCHE P06276 3/20 0.53
LMNA P02545 2/20 0.53
PLIN1 O60240 1/20 0.53
TNFRSF1A P19438 1/20 0.53
ACHE P22303 1/20 0.53
RECQL P46063 1/20 0.53
PLIN5 Q00G26 1/20 0.53
CYP1B1 Q16678 1/20 0.53
ABHD5 Q8WTS1 1/20 0.53
HDAC3 O15379 2/20 0.52
HDAC4 P56524 2/20 0.52
HDAC1 Q13547 2/20 0.52
HDAC7 Q8WUI4 2/20 0.52
HDAC2 Q92769 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3000241 1.00 MAPT (0.54) MAPTKMT2AALDH1A1MEN1NPSR1
SCHEMBL2998560 0.95 MAPT (0.52) MAPTKMT2AALDH1A1MEN1NPSR1
SCHEMBL2998570 0.95 MAPT (0.52) MAPTKMT2AALDH1A1MEN1NPSR1
SCHEMBL2999419 0.94 MGLL (0.51) MAPTKMT2AALDH1A1MEN1NPSR1
SCHEMBL2990669 0.94 MGLL (0.51) MAPTKMT2AALDH1A1MEN1NPSR1
SCHEMBL2990675 0.94 MGLL (0.51) MAPTKMT2AALDH1A1MEN1NPSR1
SCHEMBL3002222 0.94 MGLL (0.51) MAPTKMT2AALDH1A1MEN1NPSR1
SCHEMBL2989410 0.94 MGLL (0.51) MAPTKMT2AALDH1A1MEN1NPSR1
SCHEMBL2989413 0.94 MGLL (0.51) MAPTKMT2AALDH1A1MEN1NPSR1
SCHEMBL2999423 0.94 MGLL (0.51) MAPTKMT2AALDH1A1MEN1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7787085-B2 Optical alignment method and liquid crystal display element JSR CORPORATION (JP) 2010-08-31 US disclosed
US-20080123046-A1 OPTICAL ALIGNMENT METHOD AND LIQUID CRYSTAL DISPLAY ELEMENT JSR CORPORATION (JP) 2008-05-29 US disclosed
US-7074344-B2 Liquid crystal aligning agent and liquid crystal display element JSR CORPORATION (JP) 2006-07-11 US disclosed
US-20050259203-A1 Optical alignment method and liquid crystal display element JSR CORPORATION (JP) 2005-11-24 US disclosed
EP-1353217-A1 Optical alignment method and liquid crystal display element JSR Corporation (JP) 2003-10-15 EP disclosed
US-20030087045-A1 Liquid crystal aligning agent and liquid crystal display element JSR CORPORATION (JP) 2003-05-08 US disclosed