SCHEMBL30002382

SCHEMBL30002382

C=CCc1cc(C(C)(C)c2ccc(Oc3ccc(S(=O)(=O)c4ccc(Oc5ccc(C(C)(C)c6ccc(OC#N)c(CC=C)c6)cc5)cc4)cc3)cc2)ccc1OC#N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.36
FFAR4 Q5NUL3 1/20 0.33
HTT P42858 3/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
XBP1 P17861 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32
MDM2 Q00987 1/20 0.32
HSD17B10 Q99714 1/20 0.32
SLC22A12 Q96S37 1/20 0.32
NR1I2 O75469 1/20 0.32
HSD11B1 P28845 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21533300 1.00 POLB (0.36) POLBFFAR4HTTTDP1L3MBTL1
SCHEMBL26908302 0.87 POLB (0.42) POLBFFAR4HTTTDP1L3MBTL1
SCHEMBL29032524 0.85 POLB (0.37) POLBFFAR4HTTTDP1L3MBTL1
SCHEMBL3420813 0.84 ELANE (0.36) L3MBTL1ALDH1A1MAPTMAPK1HSD17B10
SCHEMBL29664254 0.84 ELANE (0.36) L3MBTL1ALDH1A1MAPTMAPK1HSD17B10
SCHEMBL10259773 0.82 FFAR4 (0.43) FFAR4HTTTDP1L3MBTL1SMN1; SMN2
SCHEMBL21177757 0.79 POLB (0.55) POLBFFAR4L3MBTL1ALDH1A1MAPT
SCHEMBL21533302 0.79 POLB (0.36) POLBFFAR4HTTTDP1L3MBTL1
SCHEMBL2586433 0.78 HTT (0.44) POLBHTTTDP1L3MBTL1SMN1; SMN2
SCHEMBL25873132 0.75 ELANE (0.32) TDP1ALDH1A1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240247107-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2024-07-25 US disclosed
EP-4347702-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS Wacker Chemie AG (DE) 2024-04-10 EP disclosed
EP-4153658-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS Wacker Chemie AG (DE) 2023-03-29 EP disclosed
WO-2022253413-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2022-12-08 WO disclosed