SCHEMBL2586433

SCHEMBL2586433

CC(C)(c1ccc(OC#N)cc1)c1ccc(Oc2ccc(S(=O)(=O)c3ccc(Oc4ccc(C(C)(C)c5ccc(OC#N)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 6/20 0.44
SMN1; SMN2 Q16637 6/20 0.44
HSD11B1 P28845 4/20 0.41
PKM P14618 3/20 0.41
ELANE P08246 2/20 0.41
TDP1 Q9NUW8 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ALDH1A1 P00352 5/20 0.38
LMNA P02545 4/20 0.38
MAPT P10636 3/20 0.37
POLB P06746 2/20 0.37
NR3C2 P08235 1/20 0.36
GAA P10253 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
HPGD P15428 2/20 0.35
GMNN O75496 1/20 0.35
DRD1 P21728 1/20 0.35
DRD3 P35462 1/20 0.35
CCR2 P41597 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2587780 0.95 HSD11B1 (0.44) HTTSMN1; SMN2HSD11B1PKMELANE
SCHEMBL2591090 0.87 SMN1; SMN2 (0.50) HTTSMN1; SMN2PKMELANETDP1
SCHEMBL2580928 0.87 HPGD (0.42) HTTSMN1; SMN2ELANEALDH1A1LMNA
SCHEMBL25961 0.82 HPGD (0.41) HTTSMN1; SMN2ALDH1A1MAPTPOLB
SCHEMBL1555244 0.82 HPGD (0.41) HTTSMN1; SMN2ALDH1A1MAPTPOLB
SCHEMBL7789786 0.82 HPGD (0.41) HTTSMN1; SMN2ALDH1A1MAPTPOLB
SCHEMBL9355307 0.82 PKM (0.52) HTTSMN1; SMN2PKMELANETDP1
SCHEMBL185192 0.82 PKM (0.52) HTTSMN1; SMN2PKMELANETDP1
SCHEMBL17366438 0.81 PKM (0.66) HTTSMN1; SMN2HSD11B1PKMELANE
SCHEMBL822791 0.81 HTT (0.67) HTTSMN1; SMN2HSD11B1PKMELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664341-B2 Vinylbenzyl ethers of polycyclopentadiene polyphenol DOW GLOBAL TECHNOLOGIES, LLC (US) 2014-03-04 US disclosed
US-8519066-B2 Poly(allyl ethers) of polycyclopentadiene polyphenol DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-27 US disclosed
US-20130211015-A1 VINYLBENZYL ETHERS OF POLYCYCLOPENTADIENE POLYPHENOL DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-15 US disclosed
EP-2563755-A1 VINYLBENZYL ETHERS OF POLYCYCLOPENTADIENE POLYPHENOL Dow Global Technologies LLC (US) 2013-03-06 EP disclosed
EP-2563756-A1 POLY(ALLYL ETHER)S OF POLYCYCLOPENTADIENE POLYPHENOL Dow Global Technologies LLC (US) 2013-03-06 EP disclosed
US-20130041114-A1 POLY(ALLYL ETHERS) OF POLYCYCLOPENTADIENE POLYPHENOL DOW GLOBAL TECHNOLOGIES LLC (US) 2013-02-14 US disclosed
WO-2011136847-A1 POLY(ALLYL ETHER)S OF POLYCYCLOPENTADIENE POLYPHENOL DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-03 WO disclosed
WO-2011136845-A1 VINYLBENZYL ETHERS OF POLYCYCLOPENTADIENE POLYPHENOL DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-03 WO disclosed
US-6337375-B1 RESIN WITH COLOR AND FLUORESCING AGENT INTERNATIONAL BUSINESS MACHINES CORPORATION 2002-01-08 US disclosed
US-6190759-B1 ELECTRONIC PACKAGE COMPRISING DIELECTRIC LAYER AND CONDUCTIVE LAYER, SAID DIELECTRIC LAYER INCLUDING REINFORCING MATERIAL, RESIN MATERIAL SELECTED FROM EPOXY, CYANATE AND BISMALEIMIDE RESINS, COLORING AGENT, AND FLUORESCING AGENT INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-02-20 US disclosed
EP-0147548-A2 Novel polyaromatic cyanates and polytriazines prepared therefrom THE DOW CHEMICAL COMPANY (US) 1985-07-10 EP disclosed
EP-0147547-A2 Preparation of aromatic cyanates THE DOW CHEMICAL COMPANY (US) 1985-07-10 EP disclosed
US-4528366-A Production of polytriazines from aromatic polycyanates with cobalt salt of a carboxylic acid as catalyst THE DOW CHEMICAL COMPANY (US) 1985-07-09 US disclosed
WO-1985002184-A1 POLYAROMATIC CYANATES, A PROCESS FOR PREPARING THE POLYAROMATIC CYANATES, AND POLYTRIAZINES PREPARED FROM THE POLYAROMATIC CYANATES THE DOW CHEMICAL COMPANY (US) 1985-05-23 WO disclosed
WO-1985002185-A1 A PROCESS FOR THE PREPARATION OF AROMATIC CYANATES THE DOW CHEMICAL COMPANY (US) 1985-05-23 WO disclosed
US-4195132-A CROSSLINKING BY WAT OF TRIAZINE RINGS BAYER AKTIENGESELLSCHAFT (DE) 1980-03-25 US disclosed
US-4116946-A OLEFIN, CATALYST BAYER AKTIENGESELLSCHAFT (DE) 1978-09-26 US disclosed
US-4094852-A Process for the production of polytriazines in the presence of high-boiling esters BAYER AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed
US-4066577-A HIGH MOLECULAR WEIGHT POLYTRIAZINES OF SOLUBLE POLYMERIC N-CYANO-ISOUREA ETHERS BAYER AKTIENGESELLSCHAFT (DT) 1978-01-03 US disclosed
US-4031067-A Polytriazines and a process for their production BAYER AKTIENGESELLSCHAFT (DT) 1977-06-21 US disclosed